ZFIN is now using GRCz12tu for Genomic Data
Gene
arih1
- ID
- ZDB-GENE-030131-5213
- Name
- ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
- Symbol
- arih1 Nomenclature History
- Previous Names
-
- wu:fa18d01
- zgc:66364
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ubiquitin conjugating enzyme binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in Lewy body and nuclear body. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Predicted to colocalize with cullin-RING ubiquitin ligase complex. Orthologous to human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66364 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR002867 | IBR domain |
| Domain | IPR044066 | TRIAD supradomain |
| Domain | IPR045840 | Ariadne domain |
| Domain | IPR048962 | E3 ubiquitin-protein ligase ARIH1-like, UBA-like domain |
| Family | IPR031127 | E3 ubiquitin ligase RBR family |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ariadne domain | E3 ubiquitin ligase RBR family | E3 ubiquitin-protein ligase ARIH1-like, UBA-like domain | IBR domain | TRIAD supradomain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6PFJ9 | InterPro | 527 | |||||||
| UniProtKB:B2GS68 | InterPro | 527 | |||||||
| UniProtKB:A0A8M3AKC6 | InterPro | 349 | |||||||
| UniProtKB:A0AC58HSP0 | InterPro | 349 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers