Gene
tecrb
- ID
- ZDB-GENE-030131-5154
- Name
- trans-2,3-enoyl-CoA reductase b
- Symbol
- tecrb Nomenclature History
- Previous Names
-
- tecr
- cb250 (1)
- gpsn2
- mg:db03b10
- sb:cb250
- wu:fj63b12
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have oxidoreductase activity. Predicted to be involved in very long-chain fatty acid biosynthetic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in several structures, including digestive system; eye; forebrain; musculature system; and solid lens vesicle. Orthologous to human TECR (trans-2,3-enoyl-CoA reductase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb250 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 14 | Alliance | Intellectual developmental disorder, autosomal recessive 14 | 614020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal | 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase | TECR-like, N-terminal domain | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q7T390
|
308 | ||||
|
UniProtKB:A0A8M9QLQ8
|
348 |
Interactions and Pathways
No data available
Plasmids
No data available