Gene
pif1
- ID
- ZDB-GENE-030131-4928
- Name
- PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
- Symbol
- pif1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable 5'-3' DNA helicase activity. Predicted to be involved in DNA duplex unwinding and DNA replication. Predicted to act upstream of or within DNA damage response and telomere maintenance. Predicted to be located in mitochondrion and nucleus. Predicted to be active in replication fork. Is expressed in ectoderm; head; optic tectum; pectoral fin musculature; and proliferative region. Orthologous to human PIF1 (PIF1 5'-to-3' DNA helicase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb934 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR010285 | DNA helicase Pif1-like, DEAD-box helicase domain |
| Domain | IPR049163 | DNA helicase Pif1-like, 2B domain |
| Family | IPR048293 | DNA helicase PIF1/RRM3/pfh1 |
| Family | IPR051055 | PIF1 DNA helicase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | DNA helicase Pif1-like, 2B domain | DNA helicase Pif1-like, DEAD-box helicase domain | DNA helicase PIF1/RRM3/pfh1 | PIF1 DNA helicase | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZV90 | InterPro | 639 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available