Gene

atp6v0a1a

ID
ZDB-GENE-030131-3027
Name
ATPase H+ transporting V0 subunit a1a
Symbol
atp6v0a1a Nomenclature History
Previous Names
  • atp6v0a1
  • wu:fc25b09
  • zgc:76965
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have ATPase binding activity and proton-transporting ATPase activity, rotational mechanism. Involved in autophagosome maturation; neural crest cell migration; and phagolysosome assembly. Predicted to localize to plasma membrane and vacuolar proton-transporting V-type ATPase complex. Orthologous to human ATP6V0A1 (ATPase H+ transporting V0 subunit a1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Peri et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atp6v0a1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 104 Alliance Developmental and epileptic encephalopathy 104 619970
Neurodevelopmental disorder with epilepsy and brain atrophy 619971
Associated With atp6v0a1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002490 V-type ATPase, V0 complex, 116kDa subunit family
Family IPR026028 ATPase, V0 complex, subunit 116kDa, eukaryotic
Domain Details Per Protein
Protein Length ATPase, V0 complex, subunit 116kDa, eukaryotic V-type ATPase, V0 complex, 116kDa subunit family
UniProtKB:A0A8M2BB25 840
UniProtKB:Q6NY92 834
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA atp6v0a1a-201 (1) Ensembl 3,556 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-atp6v0a1 polyclonal IgG Rabbit
  • WB
Santa Cruz Biotechnology, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations