ZFIN ID: ZDB-GENE-030131-3027
Gene Name: ATPase H+ transporting V0 subunit a1a
Gene Symbol: atp6v0a1a    Nomenclature History

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Previous Names: atp6v0a1, wu:fc25b09, zgc:76965

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have ATPase binding activity and proton-transporting ATPase activity, rotational mechanism. Involved in autophagosome maturation; neural crest cell migration; and phagolysosome assembly. Predicted to localize to plasma membrane and vacuolar proton-transporting V-type ATPase complex. Orthologous to human ATP6V0A1 (ATPase H+ transporting V0 subunit a1).
Genome Resources: Alliance (1),  Gene:324307 (1),  Ensembl(GRCz11):ENSDARG00000020847 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Peri et al., 2008
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015092Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19970 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19971 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26028 Point Mutation Unknown Premature Stop ENU
    sa33125 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-atp6v0a1a N/A 3
    MO2-atp6v0a1a N/A 3
    DISEASE ASSOCIATED WITH atp6v0a1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH atp6v0a1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process autophagosome maturation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function proton transmembrane transporter activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA atp6v0a1a-201 (1)    Ensembl 3556
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-atp6v0a1 polyclonal IgG Rabbit WB Santa Cruz Biotechnology, Inc.
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp6v0a1a No data available
    MARKER RELATIONSHIPS
    atp6v0a1a Contained in: [BAC] CH211-222D3 (1)
    atp6v0a1a Encodes: [EST] fc25b09
    [cDNA] MGC:76965 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212672 (1) 3570 nt
    Genomic GenBank:BX470185 (1) 198900 nt
    Select Tool
    Polypeptide UniProtKB:F1QEY7 (1) 834 aa
    Sequence Information (all 13)
    ORTHOLOGY for atp6v0a1a ( Chr: 3 )
    CITATIONS (29)