Gene
sv2bb
- ID
- ZDB-GENE-030131-2789
- Name
- synaptic vesicle glycoprotein 2Bb
- Symbol
- sv2bb Nomenclature History
- Previous Names
-
- sv2b
- wu:fc17h05
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable transmembrane transporter activity. Predicted to act upstream of or within chemical synaptic transmission; neurotransmitter transport; and transmembrane transport. Predicted to be located in cytoplasmic vesicle; membrane; and synapse. Predicted to be active in synaptic vesicle membrane. Is expressed in central nervous system; lateral line ganglion; neurons; retinal ganglion cell layer; and retinal inner nuclear layer. Orthologous to human SV2B (synaptic vesicle glycoprotein 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR005829 | Sugar transporter, conserved site |
| Domain | IPR020846 | Major facilitator superfamily domain |
| Family | IPR005828 | Major facilitator, sugar transporter-like |
| Family | IPR011701 | Major facilitator superfamily |
| Family | IPR022308 | Synaptic vesicle protein SV2 |
1 - 5 of 7 Show all
Domain Details Per Protein
| Protein | Length | Major facilitator, sugar transporter-like | Major facilitator superfamily | Major facilitator superfamily domain | MFS transporter superfamily | Pentapeptide repeat | Sugar transporter, conserved site | Synaptic vesicle protein SV2 |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:X1WCQ3
|
687 |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-52P2 | ZFIN Curated Data | |
| Encodes | EST | fc17h05 | ||
| Encodes | EST | fq34a02 | Rauch et al., 2003 |
1 - 3 of 3
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005161518 (1) | 3850 nt | ||
| Genomic | GenBank:CR854891 (1) | 135337 nt | ||
| Polypeptide | UniProtKB:X1WCQ3 (1) | 687 aa |
- Pedersen, J.E., Bergqvist, C.A., Larhammar, D. (2019) Evolution of vertebrate nicotinic acetylcholine receptors. BMC Evolutionary Biology. 19:38
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Hensley, M.R., Emran, F., Bonilla, S., Zhang, L., Zhong, W., Grosu, P., Dowling, J.E., and Leung, Y.F. (2011) Cellular Expression of Smarca4 (Brg1)-regulated Genes in Zebrafish Retinas. BMC Developmental Biology. 11(1):45
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
1 - 5 of 5
Show