ZFIN is now using GRCz12tu for Genomic Data
Gene
trim33
- ID
- ZDB-GENE-030131-2773
- Name
- tripartite motif containing 33
- Symbol
- trim33 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable transcription coregulator activity and ubiquitin protein ligase activity. Acts upstream of or within several processes, including hemopoiesis; leukocyte chemotaxis; and regulation of transcription elongation by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including blood vessel; germ ring; gonad; intermediate cell mass of mesoderm; and nervous system. Human ortholog(s) of this gene implicated in developmental dysplasia of the hip. Orthologous to human TRIM33 (tripartite motif containing 33).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1085 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 32 figures from 9 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Developmental dysplasia of the hip 4 | 621311 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR000315 | B-box-type zinc finger |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR003649 | B-box, C-terminal |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | B-box, C-terminal | B-box-type zinc finger | Bromodomain | Bromodomain-like superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8Q2E8 | InterPro | 1159 | |||||||||||
| UniProtKB:B0S5U2 | InterPro | 1176 | |||||||||||
| UniProtKB:Q6E2N3 | InterPro | 1163 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trim33-201
(1)
|
Ensembl | 4,048 nt | ||
| mRNA |
trim33-202
(1)
|
Ensembl | 819 nt | ||
| mRNA |
trim33-203
(1)
|
Ensembl | 3,480 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers