Gene
rpl3
- ID
- ZDB-GENE-030131-1291
- Name
- ribosomal protein L3
- Symbol
- rpl3 Nomenclature History
- Previous Names
-
- wu:fa99g02
- wu:fb65e09
- zgc:110350
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity. Involved in exocrine pancreas development. Predicted to localize to cytosolic large ribosomal subunit. Used to study Shwachman-Diamond syndrome. Is expressed in eye; liver; and pancreas. Orthologous to human RPL3 (ribosomal protein L3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110350 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Shwachman-Diamond syndrome | rpl3hi2437Tg/+; jh1Tg; jh2Tg | standard conditions | Provost et al., 2012 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019926 | Large ribosomal subunit protein uL3, conserved site |
| Family | IPR000597 | Large ribosomal subunit protein uL3 |
| Family | IPR045077 | Large ribosomal subunit protein uL3, archaeal/eukaryotic-type |
| Homologous_superfamily | IPR009000 | Translation protein, beta-barrel domain superfamily |
| Homologous_superfamily | IPR044892 | Ribosomal protein L3, domain 3, archaeal-type superfamily |
Domain Details Per Protein
| Protein | Length | Large ribosomal subunit protein uL3 | Large ribosomal subunit protein uL3, archaeal/eukaryotic-type | Large ribosomal subunit protein uL3, conserved site | Ribosomal protein L3, domain 3, archaeal-type superfamily | Translation protein, beta-barrel domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6Q418
|
403 | |||||
|
UniProtKB:A0A2R8Q924
|
403 |
Interactions and Pathways
No data available
Plasmids
No data available