Gene

kbtbd8

ID

ZDB-GENE-030114-8

Name

kelch repeat and BTB (POZ) domain containing 8

Symbol

kbtbd8 Nomenclature History

Previous Names

cb672 (1)
takrp
wu:fc57a10
zgc:152950

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to be involved in neural crest cell development; neural crest formation; and protein monoubiquitination. Predicted to localize to Cul3-RING ubiquitin ligase complex. Is expressed in several structures, including adaxial cell; diencephalon; neural plate; primordial germ cell; and tail bud. Orthologous to human KBTBD8 (kelch repeat and BTB domain containing 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb672 (18 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kbtbd8 Human Ortholog

No data available

Associated With kbtbd8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000210	BTB/POZ domain
Domain	IPR011705	BTB/Kelch-associated
Domain	IPR028764	Kelch repeat and BTB domain-containing protein 8, BTB/POZ domain
Family	IPR017096	BTB-kelch protein
Homologous_superfamily	IPR011333	SKP1/BTB/POZ domain superfamily
Homologous_superfamily	IPR015915	Kelch-type beta propeller
Repeat	IPR006652	Kelch repeat type 1