FIGURE SUMMARY
Title

Silver Nanoparticles in Zebrafish (Danio rerio) Embryos: Uptake, Growth and Molecular Responses

Authors
Qiang, L., Arabeyyat, Z.H., Xin, Q., Paunov, V.N., Dale, I.J.F., Lloyd Mills, R.I., Rotchell, J.M., Cheng, J.
Source
Full text @ Int. J. Mol. Sci.
Figure 1

Transmission electron microscopy images of S4 (A) and S10 (B) silver nanoparticles (AgNPs). Histograms of the size distribution for S4 (C) and S10 (D).
Figure 2

Representative phenotypes of zebrafish embryos upon exposure to AgNP concentration of (B) 1.925 mg/L, compared with the control (A) at 72 hpf. Scale bar = 500 μm.
Figure 3

Percentage change of (A) body length and (B) yolk sac area of zebrafish embryos following exposure to AgNPs (at 0.481, 0.963, 1.925 mg/L) compared with the control (without AgNPs) at 72 hpf. Values represent mean ± standard error. Results have been normalised on control (0 µg/L). The body length of control embryos was (3.618 ± 0.047) mm (S4) and (3.603± 0.009) mm (S10), and the yolk sac area of control embryos was (0.328 ± 0.014) mm2 (S4) and (0.333 ± 0.011) mm2 (S10). * significant difference between samples and the control groups using one-way ANOVA. * p < 0.05. n = 4.
Figure 4

Silver content in wet weight of fish embryos exposed to AgNPs from 4 to 96 hpf. Values represent mean ± standard error. * significant difference between samples and the control groups using one-way ANOVA. * p < 0.05. n = 4.
Figure 5

qPCR mRNA transcript levels for (A) SOD2, (B) CAT, (C) HIF4, (D) Pxmp2 and (E) Muc genes in zebrafish embryos at 96 hpf following exposure to AgNO3 (18 µg/L Ag+), S4 AgNPs (1.925 mg/L), and S10 AgNPs (1.925 mg/L). Values represent mean ± standard error. * significant difference between samples and the control groups using either two-sample t-test or Mann–Whitney test. * p < 0.05. n = 4.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.
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