Gene

slc33a1

ID

ZDB-GENE-040426-1241

Name

solute carrier family 33 member 1

Symbol

slc33a1 Nomenclature History

Previous Names

zgc:63693

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have solute:proton symporter activity. Involved in central nervous system neuron axonogenesis and negative regulation of BMP signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 42. Orthologous to human SLC33A1 (solute carrier family 33 member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:63693 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc33a1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hereditary spastic paraplegia 42	Alliance	Spastic paraplegia 42, autosomal dominant	612539
		Huppke-Brendel syndrome	614482

Associated With slc33a1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR004752	AmpG-like permease/Acetyl-coenzyme A transporter 1
Family	IPR024371	Acetyl-coenzyme A transporter 1-like
Homologous_superfamily	IPR036259	MFS transporter superfamily