ZFIN Lab: Kapp Lab

ZFIN ID: ZDB-LAB-240202-2

Kapp Lab

PI/Director:	Kapp, Friedrich
Contact Person:	Kapp, Friedrich
Email:	Friedrich.kapp@uniklinik-freiburg.de
URL:	https://www.research-for-children.de/groups/kapp/?portfolioCats=24
Address:	Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center – University of Freiburg, Mathildenstraße 1, 79106 Freiburg, Germany
Country:	Germany
Phone:	49 761 270 77548
Fax:
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Cordes, Johanna Graduate Student	Mahammadzade, Nagi Graduate Student	Oppenheimer, Aviv Graduate Student
Suchant, Daniela Technical Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Kapp, F.G., Kretschmer, S., Beckmann, C.C.A., Wäsch, L., Molitor, A., Carapito, R., Schubert, M., Lucas, N., Conrad, S., Poignant, S., Isidor, B., Rohlfs, M., Kisaarslan, A.P., Schanze, D., Zenker, M., Schmitt-Graeff, A., Strahm, B., Peters, A., Yoshimi, A., Driever, W., Zillinger, T., Günther, C., Maharana, S., Guan, K., Klein, C., Ehl, S., Niemeyer, C.M., Unal, E., Bahram, S., Hauck, F., Lee-Kirsch, M.A., Speckmann, C. (2023) C-terminal variants in CDC42 drive type I interferon-dependent autoinflammation in NOCARH syndrome reversible by ruxolitinib. Clinical immunology (Orlando, Fla.). 256:109777109777

Siebert, J., Schneider, M., Reuter-Schmitt, D., Würtemberger, J., Neubüser, A., Driever, W., Hettmer, S., Kapp, F.G. (2022) Rhabdomyosarcoma xenotransplants in zebrafish embryos. Pediatric blood & cancer. 70(1):e30053

Bell, L.M., Holm, A., Matysiak, U., Driever, W., Rößler, J., Schanze, D., Wieland, I., Niemeyer, C.M., Zenker, M., Kapp, F.G. (2021) Functional assessment of two variants of unknown significance in TEK by endothelium-specific expression in zebrafish embryos. Human molecular genetics. 31(1):10-17

Piragyte, I., Clapes, T., Polyzou, A., Klein Geltink, R.I., Lefkopoulos, S., Yin, N., Cauchy, P., Curtis, J.D., Klaeylé, L., Langa, X., Beckmann, C.C.A., Wlodarski, M.W., Müller, P., Van Essen, D., Rambold, A., Kapp, F.G., Mione, M., Buescher, J.M., Pearce, E.L., Polyzos, A., Trompouki, E. (2018) A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nature communications. 9:3090

Kapp, F.G., Perlin, J.R., Hagedorn, E.J., Gansner, J.M., Schwarz, D.E., O'Connell, L.A., Johnson, N.S., Amemiya, C., Fisher, D.E., Wölfle, U., Trompouki, E., Niemeyer, C.M., Driever, W., Zon, L.I. (2018) Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche. Nature. 558(7710):445-448