ZFIN Lab: Xiaohong Duan Lab

ZFIN ID: ZDB-LAB-170209-14

ZFIN ID: ZDB-LAB-170209-14

Xiaohong Duan Lab

PI/Director:	Duan, Xiaohong
Contact Person:
Email:	xhduan@fmmu.edu.cn
URL:	http://kqsw.fmmu.edu.cn/english.htm
Address:	Department of Oral Biology Clinic of Oral Rare and Genetic Diseases School of Stomatology The Fourth Military Medical University 145 West Changle Road Xi'an, Shaanxi 710032 CHINA
Country:	China
Phone:	+86 29 84776169
Fax:	+86 29 84776169
Line Designation:	None assigned

GENOMIC FEATURES ORIGINATING FROM THIS LAB No data available

STATEMENT OF RESEARCH INTERESTS

We are interested in the genetic disorders of craniofacial and oral regions and their molecular mechanisms involving tooth and bone development. We focus on the ion channels or transporters and related channelopathies. We use zebrafish to help us to understand the genetic diseases and common diseases of craniofacial and oral regions. We have very good zebrafish larva models of dental fluorosis.
Besides zebrafish model, we also use mouse and other in vitro methods to help us understand the molecular mechanism of craniofacial and oral disorders.

LAB MEMBERS

Hao, Ying Graduate Student	Li, Lin Graduate Student	Liu, Jin Graduate Student
Yang, Shaoqing Research Staff	Zhang, Xueni Research Staff	Zhang, Yanli Research Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Zhang, Y., Ji, D., Li, L., Yang, S., Zhang, H., Duan, X. (2019) ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth. Theranostics. 9:1387-1400

Li, L., Yang, S., Zhang, Y., Ji, D., Jin, Z., Duan, X. (2018) ATP6V1H regulates the growth and differentiation of bone marrow stromal cells. Biochemical and Biophysical Research Communications. 502(1):84-90

Zhao, W., Zhang, Y., Yang, S., Hao, Y., Wang, Z., Duan, X. (2018) Analysis of two transcript isoforms of vacuolar ATPase subunit H in mouse and zebrafish. Gene. 638:66-75

Zhang, Y., Huang, H., Zhao, G., Yokoyama, T., Vega, H., Huang, Y., Sood, R., Bishop, K., Maduro, V., Accardi, J., Toro, C., Boerkoel, C.F., Lyons, K., Gahl, W.A., Duan, X., Malicdan, M.C., Lin, S. (2017) ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13. PLoS Genetics. 13:e1006481

Zhang, Y., Ke, Y., Zheng, X., Liu, Q., Duan, X. (2017) Correlation between genotype and phenotype in three families with Peutz-Jeghers Syndrome. Experimental and Therapeutic Medicine. 13(2):507-514

Pang, M., Lin, X., Liu, J., Guo, C., Gao, S., Du, H., Lu, C., Liu, Y. (2016) Identification of Aeromonas hydrophila Genes Preferentially Expressed after Phagocytosis by Tetrahymena and Involvement of Methionine Sulfoxide Reductases.. Frontiers in cellular and infection microbiology. 6:199

Zhang, Y., Zhang, Y., Zheng, X., Xu, R., He, H., Duan, X. (2016) Grading and quantification of dental fluorosis in zebrafish larva. Archives of oral biology. 70:16-23

Wang, H., Pan, M., Ni, J., Zhang, Y., Zhang, Y., Gao, S., Liu, J., Wang, Z., Zhang, R., He, H., Wu, B., Duan, X. (2016) ClC-7 Deficiency Impairs Tooth Development and Eruption. Scientific Reports. 6:19971

Jiao, Y., Zhu, B., Chen, J., Duan, X. (2015) Fluorescent Sensing of Fluoride in Cellular System. Theranostics. 5(2):173-187

Zhang, Y., Zhang, C., Peng, G., Duan, X. (2014) Characteristics of craniofacial bone development of zebrafish. Kou qiang yi xue yan jiu = Journal of oral science research. 30(2):97-99