ZFIN ID: ZDB-LAB-120608-1
Gang Peng Lab
PI/Director: Peng, Gang
Contact Person: Gao, Jingxia
Email: gaojingxia@fudan.edu.cn
Address: Room 1012 Mingdao Building Laboratory of Nervous System Development and Animal Behavior Institutes of Brain Science, Fudan University 138 Yixueyuan Road Shanghai 200032 China
Country: China
Phone: 86-21-54237818
Fax: 86-21-54237643
Line Designation: None assigned


Gang Peng is a Principal Investigator at the Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University. He received his B.Sc. degree in Peking University in 1996 and his Ph.D. degree in Biochemistry and Molecular Biology from PennState University in 2002. He was a postdoctoral research associate in Dr. Monte Westerfield’s laboratory in the Institute of Neuroscience in the University of Oregon between 2002 and 2008. He joined the Institutes of Brain Science and the State Key Laboratory of Medical Neurobiology, Fudan University in 2008.
Our research has been focused on the molecular mechanisms underlying nervous system development and behavior in the zebrafish Danio rerio. The long term goal of his research is two-fold: to determine how external stimuli are processed by the neural circuits in the zebrafish brain to direct its adaptive behaviors; and to learn how the central neural circuits responsible for these behaviors are specified genetically and molecularly. In addition, his research group is generating zebrafish models of nervous system diseases and mental disorders, with the goal to provide novel routes for the understanding of the genetic underpinnings and the treatment of those diseases.

Chen, Sijie Graduate Student Sun, Liu Graduate Student Wang, Fenghua Graduate Student
Yang, Bin Graduate Student Zhang, Changwen Graduate Student Zhang, Hefei Graduate Student
Gao, Jingxia Research Staff Zhang, Cuizhen Research Staff

Zhang, H., Zhang, Q., Gao, G., Wang, X., Wang, T., Kong, Z., Wang, G., Zhang, C., Wang, Y., Peng, G. (2018) UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling. PLoS Genetics. 14:e1007583
Gao, J., Stevenson, T.J., Douglass, A.D., Barrios, J.P., Bonkowsky, J.L. (2018) The Midline Axon Crossing Decision Is Regulated through an Activity-Dependent Mechanism by the NMDA Receptor. eNeuro. 5(2)
Wang, X., Chen, S., Zhang, W., Ren, Y., Zhang, Q., Peng, G. (2017) Dissection of Larval Zebrafish Gonadal Tissue. Journal of visualized experiments : JoVE. (122)
Zhang, B.B., Yao, Y.Y., Zhang, H.F., Kawakami, K., Du, J.L. (2017) Left Habenula Mediates Light-Preference Behavior in Zebrafish via an Asymmetrical Visual Pathway. Neuron. 93(4):914-928.e4
Zhang, C., Ellis, J.L., Yin, C. (2016) Inhibition of vascular endothelial growth factor signaling facilitates liver repair from acute ethanol-induced injury in zebrafish. Disease models & mechanisms. 9(11):1383-1396
Chen, S., Zhang, H., Wang, F., Zhang, W., Peng, G. (2016) nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation. Molecular and Cellular Endocrinology. 433:105-16
Milash, B., Gao, J., Stevenson, T.J., Son, J.H., Dahl, T., Bonkowsky, J.L. (2016) Temporal Dysynchrony in brain connectivity gene expression following hypoxia. BMC Genomics. 17:334
Chen, F., Chen, S., Liu, S., Zhang, C., Peng, G. (2015) Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice test. Neuropharmacology. 95:226-33
Sun, L., Chen, F., Peng, G. (2015) Conserved Noncoding Sequences Regulate lhx5 Expression in the Zebrafish Forebrain. PLoS One. 10:e0132525
Qiao, J., Cui, S.J., Xu, L.L., Chen, S.J., Yao, J., Jiang, Y.H., Peng, G., Fang, C.Y., Yang, P.Y., Liu, F. (2015) Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells. Oncotarget. 6(2):1171-89
Zhang, Y., Zhang, C., Peng, G., Duan, X. (2014) Characteristics of craniofacial bone development of zebrafish. Journal of Oral Science Research. 30(2):97-99
Yang, B., Peng, G., and Gao, J. (2013) Expression of unc5 family genes in zebrafish brain during embryonic development. Gene Expression Patterns. 13(8):311-8
Dong, M., Zhu, L., Shao, B., Zhu, S., Wang, J., Xie, H., Wang, J., and Wang, F. (2013) The effects of endosulfan on cytochrome P450 enzymes and glutathione S-transferases in zebrafish (Danio rerio) livers. Ecotoxicology and environmental safety. 92:1-9
Zhang, C., Gao, J., Zhang, H., Sun, L., and Peng, G. (2012) Robo2-Slit and Dcc-Netrin1 Coordinate Neuron Axonal Pathfinding within the Embryonic Axon Tracts. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(36):12589-12602
Gao, J., Zhang, C., Yang, B., Sun, L., Zhang, C., Westerfield, M., and Peng, G. (2012) Dcc Regulates Asymmetric Outgrowth of Forebrain Neurons in Zebrafish. PLoS One. 7(5):e36516
Delaurier, A., Eames, B.F., Blanco-Sánchez, B., Peng, G., He, X., Swartz, M.E., Ullmann, B., Westerfield, M., and Kimmel, C.B. (2010) Zebrafish sp7:EGFP: A transgenic for studying otic vesicle formation, skeletogenesis, and bone regeneration. Genesis (New York, N.Y. : 2000). 48(8):505-511
Schlueter, P.J., Peng, G., Westerfield, M., and Duan, C. (2007) Insulin-like growth factor signaling regulates zebrafish embryonic growth and development by promoting cell survival and cell cycle progression. Cell death and differentiation. 14(6):1095-1105
Peng, G., and Westerfield, M. (2006) Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists. Development (Cambridge, England). 133(16):3191-3200