ZFIN ID: ZDB-LAB-100818-1
Lewis Lab - Syracuse
PI/Director: Lewis, Katharine E.
Contact Person: Lewis, Katharine E.
Email: kelewi02@syr.edu
URL: http://biology.syr.edu/faculty/lewis/lewis.htm
Address: Department of Biology Syracuse University 107 College Place Syracuse NY 13244 USA
Country: United States
Phone: 315 443 5902
Line Designation: su

Show all 15 genomic features

Specification and patterning of spinal cord neurons and neuronal circuitry; dorsal-ventral neural tube patterning; Evolution of vertebrate spinal cord patterning and function.


England, S.J., Rusnock, A.K., Mujcic, A., Kowalchuk, A., de Jager, S., Hilinski, W.C., Juárez-Morales, J.L., Smith, M.E., Grieb, G., Banerjee, S., Lewis, K.E. (2023) Molecular analyses of zebrafish V0v spinal interneurons and identification of transcriptional regulators downstream of Evx1 and Evx2 in these cells. Neural Development. 18:88
Haws, W., England, S., Grieb, G., Susana, G., Hernandez, S., Mirer, H., Lewis, K. (2023) Analyses of binding partners and functional domains for the developmentally essential protein Hmx3a/HMX3. Scientific Reports. 13:11511151
Juárez-Morales, J.L., Weierud, F., England, S.J., Demby, C., Santos, N., Grieb, G., Mazan, S., Lewis, K.E. (2021) Evolution of lbx spinal cord expression and function. Evolution & development. 23(5):404-422
England, S.J., Cerda, G.A., Kowalchuk, A., Sorice, T., Grieb, G., Lewis, K.E. (2020) Hmx3a Has Essential Functions in Zebrafish Spinal Cord, Ear and Lateral Line Development. Genetics. 216(4):1153-1185
Duggan, K.L., Morris, M., Bhatia, S.K., Khachan, M.M., Lewis, K.E. (2019) Effects of Cationic Polyacrylamide and Cationic Starch on Aquatic Life. Journal of hazardous, toxic and radioactive waste. 23(4):
Hartwell, R.D., England, S.J., Monk, N.A.M., van Hateren, N.J., Baxendale, S., Marzo, M., Lewis, K.E., Whitfield, T.T. (2019) Anteroposterior patterning of the zebrafish ear through Fgf- and Hh-dependent regulation of hmx3a expression. PLoS Genetics. 15:e1008051
Andrzejczuk, L.A., Banerjee, S., England, S.J., Voufo, C., Kamara, K., Lewis, K.E. (2018) Tal1, Gata2a, and Gata3 Have Distinct Functions in the Development of V2b and Cerebrospinal Fluid-Contacting KA Spinal Neurons. Frontiers in neuroscience. 12:170
Wilk, R., Ali, N., England, S.J., Lewis, K.E. (2018) Using Zebrafish to Bring Hands-On Laboratory Experiences to Urban Classrooms. Zebrafish. 15(2):156-178
Juárez-Morales, J.L., Martinez-De Luna, R.I., Zuber, M.E., Roberts, A., Lewis, K.E. (2017) Zebrafish transgenic constructs label specific neurons in Xenopus laevis spinal cord and identify frog V0v spinal neurons. Developmental Neurobiology. 77(8):1007-1020
England, S.J., Campbell, P.C., Banerjee, S., Swanson, A.J., Lewis, K.E. (2017) Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes.. Frontiers in cell and developmental biology. 5:5
Hilinski, W.C., Bostrom, J.R., England, S.J., Juárez-Morales, J.L., de Jager, S., Armant, O., Legradi, J., Strähle, U., Link, B.A., Lewis, K.E. (2016) Lmx1b is required for the glutamatergic fates of a subset of spinal cord neurons. Neural Development. 11:16
Juárez-Morales, J.L., Schulte, C.J., Pezoa, S.A., Vallejo, G.K., Hilinski, W.C., England, S.J., de Jager, S., Lewis, K.E. (2016) Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism. Neural Development. 11:5
England, S., Hilinski, W., de Jager, S., Andrzejczuk, L., Campbell, P., Chowdhury, T., Demby, C., Fancher, W., Gong, Y., Lin, C., Machikas, A., Rodriguez-Larrain, G., Roman Rivera, V., and Lewis, K.E. (2014) Identifying Transcription Factors Expressed by Ventral Spinal Cord Interneurons. ZFIN Direct Data Submission.
England, S., Batista, M.F., Mich, J.K., Chen, J.K., and Lewis, K.E. (2011) Roles of Hedgehog pathway components and retinoic acid signalling in specifying zebrafish ventral spinal cord neurons. Development (Cambridge, England). 138(23):5121-5134
Schulte, C.J., Allen, C., England, S.J., Juárez-Morales, J.L., and Lewis, K.E. (2011) Evx1 is required for joint formation in zebrafish fin dermoskeleton. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(5):1240-1248
Goode, D.K., Callaway, H.A., Cerda, G.A., Lewis, K.E., and Elgar, G. (2011) Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events. Development (Cambridge, England). 138(5):879-884
Wotton, K.R., Weierud, F.K., Juárez-Morales, J.L., Alvares, L.E., Dietrich, S., and Lewis, K.E. (2009) Conservation of gene linkage in dispersed vertebrate NK homeobox clusters. Development genes and evolution. 219(9-10):481-496
Cerda, G.A., Hargrave, M., and Lewis, K.E. (2009) RNA profiling of FAC-sorted neurons from the developing zebrafish spinal cord. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(1):150-161
Batista, M.F., and Lewis, K.E. (2008) Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons. Developmental Biology. 323(1):88-97
Batista, M.F., Jacobstein, J., and Lewis, K.E. (2008) Zebrafish V2 cells develop into excitatory CiD and Notch signalling dependent inhibitory VeLD interneurons. Developmental Biology. 322(2):263-275
Wotton, K.R., Weierud, F.K., Dietrich, S., and Lewis, K.E. (2008) Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates. BMC Evolutionary Biology. 8:171
Lupo, G., Harris, W.A., and Lewis, K.E. (2006) Mechanisms of ventral patterning in the vertebrate nervous system. Nature reviews. Neuroscience. 7(2):103-114
Lewis, K.E. (2006) How do genes regulate simple behaviours? Understanding how different neurons in the vertebrate spinal cord are genetically specified. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 361(1465):45-66
Lewis, K.E., Bates, J., and Eisen, J.S. (2005) Regulation of iro3 expression in the zebrafish spinal cord. Developmental Dynamics : an official publication of the American Association of Anatomists. 232(1):140-148
Wolff, C., Roy, S., Lewis, K.E., Schauerte, H., Joerg-Rauch, G., Kirn, A., Weiler, C., Geisler, R., Haffter, P., Ingham, P.W. (2004) iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo. Genes & Development. 18(13):1565-1576
Lewis, K.E., and Eisen, J.S. (2004) Paraxial mesoderm specifies zebrafish primary motoneuron subtype identity. Development (Cambridge, England). 131(4):891-902
Lewis, K.E. and Eisen, J.S. (2003) From cells to circuits: development of the zebrafish spinal cord. Prog. Neurobiol.. 69(6):419-449
Lewis, K.E. and Eisen, J.S. (2001) Hedgehog signaling is required for primary motoneuron induction in zebrafish. Development (Cambridge, England). 128(18):3485-3495
Varga, Z.M., Amores, A., Lewis, K.E., Yan, Y.-L., Postlethwait, J.H., Eisen, J.S., and Westerfield, M. (2001) Zebrafish smoothened functions in ventral neural tube specification and axon tract formation. Development (Cambridge, England). 128(18):3497-3509
Lewis, K.E., Currie, P.D., Roy, S., Schauerte, H., Haffter, P., and Ingham, P.W. (1999) Control of muscle cell-type specification in the zebrafish embryo by hedgehog signalling. Developmental Biology. 216(2):469-480
Lewis, K.E., Concordet, J.P., and Ingham, P.W. (1999) Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to hedgehog signalling. Developmental Biology. 208:14-29
Concordet, J.P., Lewis, K.E., Moore, J.W., Goodrich, L.V., Johnson, R.L., Scott, M.P., and Ingham, P.W. (1996) Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development (Cambridge, England). 122(9):2835-2846