ubiquitin-dependent glycoprotein ERAD pathway

Term ID

GO:0097466

Synonyms

• ER-associated glycoprotein degradation
• glycoprotein ERAD
• gpERAD
• misfolded or incompletely synthesized glycoprotein catabolic process

Definition

An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component. 16079177

References

Ontology

GO: Biological Process    QuickGO    AmiGO