Search Ontology:
ChEBI

rofecoxib

Term ID
CHEBI:8887
Synonyms
  • 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
  • 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone
  • 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one
  • Ceoxx
  • Rofecoxib
  • rofecoxibum
  • Vioxx
Definition
A butenolide that is furan-2(5H)-one substituted by a phenyl group at position 3 and by a p-(methylsulfonyl)phenyl group at position 4. A selective cyclooxygenase 2 inhibitor, it was used from 1999 to 2004 for the treatment of ostoarthritis, but was withdrawn following concerns about an associated increased risk of heart attack and stroke.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from rofecoxib
Phenotype where environments contain rofecoxib
Phenotype modified by environments containing rofecoxib
Human Disease / Model Data
Citations
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