flunoxaprofen

Term ID

CHEBI:76154

Synonyms

(+)-2-(p-Fluorophenyl)-alpha-methyl-5-benzoxazoleacetic acid
(2S)-2-[2-(4-fluorophenyl)-1,3-benzoxazol-5-yl]propanoic acid
(S)-(+)-Flunoxaprofen
(S)-2-(4-Fluorophenyl)-alpha-methyl-5-benzoxazoleacetic acid
flunoxaprofen
flunoxaprofene
flunoxaprofeno
flunoxaprofenum

Definition

A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group (the S-enantiomer). Although it was shown to be effective in treatment of rheumatoid arthritis and osteoarthritis, the clinical use of flunoxaprofen was discontinued due to possible hepatotoxic side-effects.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 1,3-benzoxazoles monocarboxylic acid organofluorine compound

1,3-benzoxazoles monocarboxylic acid organofluorine compound Show first 5 Terms
has_functional_parent: propionic acid

propionic acid Show first 5 Terms
has_role: antirheumatic drug hepatotoxic agent non-steroidal anti-inflammatory drug protein kinase C agonist

antirheumatic drug hepatotoxic agent non-steroidal anti-inflammatory drug protein kinase C agonist Show first 5 Terms

Phenotype

Phenotype resulting from flunoxaprofen

Phenotype where environments contain flunoxaprofen

Phenotype modified by environments containing flunoxaprofen

Human Disease / Model Data

Citations