Search Ontology:
ChEBI

roducitabine

Term ID
CHEBI:147412
Synonyms
  • 1-[(1S,4R,5S)-2-fluoro-3-(hydroxymethyl)-4,5-dihydroxy-2-cyclopentenyl]cytosine
  • 4-amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1,2-dihydropyrimidin-2-one
  • 4-amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidin-2(1H)-one
  • fluorocyclopentenyl cytosine
  • fluorocyclopentenyl-cytosine
  • fluorocyclopentenylcytosine
  • RX 3117
  • RX-3117
  • RX3117
  • TV-1360
Definition
A triol that is (1S,2R)-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol which is substituted by a 4-amino-2-oxopyrimidin-1(2H)-yl group at position 5. It is a cytidine analog which exhibits anticancer activity in several cancers, including gemcitabine-resistant tumours.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from roducitabine
Phenotype where environments contain roducitabine
Phenotype modified by environments containing roducitabine
Human Disease Model