Search Ontology:
ChEBI
roducitabine
- Term ID
- CHEBI:147412
- Synonyms
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- 1-[(1S,4R,5S)-2-fluoro-3-(hydroxymethyl)-4,5-dihydroxy-2-cyclopentenyl]cytosine
- 4-amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1,2-dihydropyrimidin-2-one
- 4-amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidin-2(1H)-one
- fluorocyclopentenyl cytosine
- fluorocyclopentenyl-cytosine
- fluorocyclopentenylcytosine
- RX 3117
- RX-3117
- RX3117
- TV-1360
- Definition
- A triol that is (1S,2R)-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol which is substituted by a 4-amino-2-oxopyrimidin-1(2H)-yl group at position 5. It is a cytidine analog which exhibits anticancer activity in several cancers, including gemcitabine-resistant tumours.
- References
-
- CAS:865838-26-2
- KEGG:D11740
- PMID:22524616
- PMID:24048768
- PMID:24940694
- PMID:25503121
- PMID:27612203
- PMID:27906620
- PMID:27906622
- PMID:30663502
- PMID:30879349
- PMID:31262886
- PMID:32295203
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from roducitabine
Phenotype where environments contain roducitabine
Phenotype modified by environments containing roducitabine
Human Disease Model