Term Name: antimetabolite
Synonyms: antimetabolite, antimetabolites
Definition: A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
Ontology: Chebi [CHEBI:35221]

Relationships
is a type of: biochemical role
has subtype: antifolate
inverse has_role: 2-aminopurine 3-hydroxy-3-methylglutaric acid 4-thiouridine 5-bromo-2'-deoxyuridine 5-fluoroanthranilic acid 5-fluorouracil 5-iodouracil 6-aminonicotinamide 6-azauracil 6-azauridine 6-diazo-5-oxo-L-norleucine 6-propyl-2-thiouracil 8-azaguanine acivicin acyclovir allopurinol ancitabine ancitabine hydrochloride anticapsin anticapsin zwitterion azaserine azathioprine capecitabine cerulenin clofarabine cordycepin cordycepin triphosphate cytarabine D-cycloserine didanosine doxifluridine ezetimibe floxuridine fludarabine phosphate gemcitabine gemcitabine hydrochloride hydroxyurea L-2-amino-4-methoxy-trans-but-3-enoic acid L-beta-ethynylserine L-beta-ethynylserine zwitterion L-canaline L-ethionine mercaptopurine methotrexate metyrapone O-(2-aminoethyl)-L-serine oxythiamine chloride oxythiamine chloride hydrochloride oxythiamine(1+) pemetrexed pemetrexed disodium pemetrexed disodium heptahydrate pirazofurin pralatrexate purine-6-thiol ribavirin roducitabine sapacitabine stavudine tioguanine toyocamycin trifluridine tubercidin zalcitabine zidovudine