OBO ID: CHEBI:8887

Term Name:	rofecoxib		Search Ontology:
Synonyms:	3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one Ceoxx rofecoxib rofecoxibum Vioxx
Definition:	A butenolide that is furan-2(5H)-one substituted by a phenyl group at position 3 and by a p-(methylsulfonyl)phenyl group at position 4. A selective cyclooxygenase 2 inhibitor, it was used from 1999 to 2004 for the treatment of ostoarthritis, but was withdrawn following concerns about an associated increased risk of heart attack and stroke.
References:	Beilstein:8269007 CAS:162011-90-7 DrugBank:DB00533 Drug_Central:2397 KEGG:C07590 KEGG:D00568 LINCS:LSM-2482 PMID:10859630 PMID:11014111 PMID:12069696 PMID:16934051 PMID:20162413 PMID:28166217 Reaxys:8269007 Wikipedia:Rofecoxib
Ontology:	ChEBI  ( EBI )