OBO ID: CHEBI:78591
Term Name: pederin Search Ontology:
Synonyms:
  • (+)-pederin
  • (+)-pederine
  • (2S)-N-[(S)-{(2S,4R,6R)-6-[(2S)-2,3-dimethoxypropyl]-4-hydroxy-5,5-dimethyltetrahydro-2H-pyran-2-yl}(methoxy)methyl]-2-hydroxy-2-[(2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylenetetrahydro-2H-pyran-2-yl]acetamide
  • paederine
  • pederine
Definition: A polyketide and carboxamide produced by a (Pseudomonas) bacterial endosymbiont of certain rove beetles (genus Paederus). Pederin is the agent responsible for the vesicant effects (linear or Paederus dermatitis) when the beetle is crushed against the skin. It is a powerful inhibitor of protein biosynthesis and mitosis and a potent antitumour agent.
References:
Ontology: ChEBI  ( EBI )
Relationships
is a type of:
has_role:
PHENOTYPE No data available

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