polyketide

Term ID

CHEBI:26188

Synonyms

polyketide
polyketides

Definition

Natural and synthetic compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: organooxygen compound

organooxygen compound Show first 5 Terms
has subtype: (1'S,5'R)-5'-hydroxyaverantin (1'S,5'S)-5'-hydroxyaverantin (1'S,5'S)-averufin (1R,3R,6S,7E,10S,12R)-3,10,12-trimethyl-9,13,15-trioxo-16-oxatricyclo[12.2.1.0(1,6)]heptadeca-4,7,14(17)-trien-17-olate (1R,3R,6S,7E,10S,12R)-17-methoxy-3,10,12-trimethyl-16-oxatricyclo[12.2.1.0(1,6)]heptadeca-4,7,14(17)-triene-9,13,15-trione ... Show All 319 Terms

(1'S,5'R)-5'-hydroxyaverantin (1'S,5'S)-5'-hydroxyaverantin (1'S,5'S)-averufin (1R,3R,6S,7E,10S,12R)-3,10,12-trimethyl-9,13,15-trioxo-16-oxatricyclo[12.2.1.0(1,6)]heptadeca-4,7,14(17)-trien-17-olate (1R,3R,6S,7E,10S,12R)-17-methoxy-3,10,12-trimethyl-16-oxatricyclo[12.2.1.0(1,6)]heptadeca-4,7,14(17)-triene-9,13,15-trione (2R)-2-[(9aR)-9a-methyl-3-octanoyl-2,9-dioxo-6-[(E)-prop-1-enyl]uro[3,2-g]isoquinolin-7-yl]butanedioic acid (2R)-2-[(9aR)-9a-methyl-3-octanoyl-2,9-dioxo-6-[(E)-prop-1-enyl]uro[3,2-g]isoquinolin-7-yl]propanoic acid (2R,4S,6E,8E,10E)-1-(4-methoxy-5-methylidene-2-oxo-2,5-dihydrofuran-3-yl)-2,4-dimethyldodeca-6,8,10-triene-1,5-dione (2S)-2-[(9aR)-9a-methyl-3-octanoyl-2,9-dioxo-6-[(E)-prop-1-enyl]uro[3,2-g]isoquinolin-7-yl]butanedioic acid (2S)-2-[(9aR)-9a-methyl-3-octanoyl-2,9-dioxo-6-[(E)-prop-1-enyl]uro[3,2-g]isoquinolin-7-yl]propanoic acid (3R,5R)-cis-5-methyl-3-(2-oxobutyl)-dihydrofuran-2-one (3R,5S,8E,10E,12E)-3,5,7-trihydroxynonadeca-8,10,12-trienal (3Z)-3-[(2E,6R,8E,10E,12E)-1-hydroxy-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraen-1-ylidene]-5-(2-methylpropyl)-2,3-dihydro-1H-pyrrol-2-one (4R,6R)-6-{2-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-4-hydroxyoxan-2-one (5S)-3-[(1S,2R,4aR,6R,8aS)-2-(but-2-en-2-yl)-3,4a,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalene-1-carbonyl]-5-(2-methylpropyl)-2,5-dihydro-1H-pyrrol-2-one (5S)-3-[(2E,6R,8E,10E,12E)-2,6-dimethyltetradeca-2,8,10,12-tetraenoyl]-5-(hydroxymethyl)-2,4-dioxopyrrolidin-3-ide (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one (5S)-5-[(2R)-2-carboxylato-2-hydroxy-2-methylethyl]-2,4-dioxo-3-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-3-ide (5S)-5-[(2S)-2-carboxylato-2-hydroxy-2-methylethyl]-2,4-dioxo-3-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-3-ide (5S,S)-5-methyl-3-(6-methyloctyl)furan-2(5H)-one (5S,S)-5-methyl-3-(7-methylnonyl)furan-2(5H)-one (5Z)-5-(2-methylpropylidene)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one (7Z,10S,11SS,12R,13S,14R,15R,16S,17S,18E,20Z)-4,10,12,14,16-Pentahydroxy-9-(hydroxymethyl)-3,7,11,13,15,17,21-heptamethyl-23-azatricyclo[22.3.1.0~5,27~]octacosa-1(27),2,4,7,18,20,24-heptaene-6,22,26,28-tetrone (S)-5'-oxoaverantin (S)-DNPA 1,8-dihydroxynaphthalene-melanin 1-(3,4,5-trihydroxy-7-methoxynaphthalen-2-yl)propan-2-one 2,4-dihydroxy-3,5,6-trimethylbenzaldehyde 2,4-dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde 2-deoxy-alpha-L-fucosylaclacinomycin S 2-hexanoyl-1,3,8-trihydroxy-6-methoxy-anthraquinone 3,5-dihydroxy-2-(1'-oxo-3'-hexadecenyl)-2-cyclohexene-1-one 3-(2,8,13,14,17,18-Hexahydroxytriacontyl)-5-methyl-2(5H)-furanone 3-(2,10-Dihydroxy-10-{6-[5-(1-hydroxytridecyl)oxolan-2-yl]oxan-2-yl}decyl)-5-methyl-2,5-dihydrofuran-2-one 3-[(17Z)-13,14-Dihydroxy-17-triaconten-1-yl]-5-methyl-2(5H)-furanone 3-[(19Z)-15,16-Dihydroxy-19-dotriaconten-1-yl]-5-methyl-2(5H)-furanone 3-{[(1S,2R,4aR,6R,8aS)-2-(but-2-en-2-yl)-3,4a,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](hydroxy)methylidene}-5-(2-methylpropyl)-2,3-dihydro-1H-pyrrol-2-one 3alpha-hydroxy-3,5-dihydromonacolin L acid 4,8-diamino-N-[1-amino-3-(carbamoylamino)-1-oxopropan-2-yl]-2,3,5,7,9-pentahydroxynonanamide 4-[(2R,4S,6E,8E,10E)-2,4-dimethyl-5-oxododeca-6,8,10-trienoyl]-2-methylidene-5-oxo-2,5-dihydrofuran-3-olate 4-coumaroyltriacetic acid lactone 4-Deoxyannoreticuin 4-hydroxy-6-(2-oxoheptyl)pyran-2-one 4-hydroxy-6-pentylpyran-2-one 4-hydroxyprotoasukamycin 6-(acylmethyl)-4-hydroxy-2H-pyran-2-one 6-[(3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl]-2,4-dihydroxy-3-methylbenzaldehyde 6-[2-(2,4-dihydroxy-6-methylphenyl)-2-oxoethyl]-4-hydroxy-pyran-2-one 6-alkyl-4-hydroxy-2H-pyran-2-one 6-ethyl-2,4-dihydroxy-3,5-dimethylbenzaldehyde 6-Hydroxydesacetyluvaricin (incorr.) 7-(2-hydroxyethyl)-monascorubramine 9-Oxoasimicinone 12-deoxynogalonic acid Acaterin aclacinomycin A aclacinomycin N aclacinomycin S aclacinomycin T aclacinomycin Y actinorhodin agglomerin F angucycline Annoglacin A Annomuricin A Annomutacin Annonisin Annonsilin A Annopentocin A Annosquacin-I, (rel)- Annosquatin-I, (rel)- Annosquatin-II, (rel)- Annotemoyin 1 ansamitocin P3 ansamycin anthracycline Asimicin Asiminenin A Asitrilobin C Asitrilobin D aspalathin asperfuranone asperlactone Asperochrin B aspyridone A aspyridone B aspyrone asukamycin Atemoyacin B atrochrysone aurafuron A auricin averantin azanigerone A azanigerone B azanigerone C azanigerone D azanigerone E azanigerone F bacillaene benzoisochromanequinone Berkchaetorubramine bullatacin butremycin cannabidiolic acid cannabigerolic acid cannabinerolic acid cercosporin chaetocyclinone A chaetocyclinone B chaetocyclinone C Chatenaytrienin 1 Chatenaytrienin 2 cis-Murisolinone cis-Reticulatacin-10-one cis-Solamin cis-Uvariamicin IB cis-Uvariamicin IV clavatol Cohaerin D Cohaerin E Cohibin A Cohibin B colibactin compactin diol lactone cordypyrone A cordypyrone B Corossoline curamycin A cyathusal A cyathusal B cyathusal C decaketide Deflectin 1a Deflectin 1b Deflectin 2a Deflectin 2b Deflectin C3 Deflectin D2 Delta(9)-tetrahydrocannabinol Delta(9)-tetrahydrocannabinolic acid demethyldeoxyspectinabilin deoxyaureothin deoxyherqueinone deoxyspectinabilin depdecin depudecin Dieporeticenin dihydro-nogalonic acid methyl ester dihydromonacolin L acid diketide dimethyl 2,2'-(9,9',10,10'-tetrahydroxy-7,7'-dimethoxy-1,1'-dioxo-3,3',4,4'-tetrahydro-[6,6'-binaphtho[2,3-c]pyran]-3,3'-diyl)diacetate Donhexocin Epomuricenin B Epomusenin A Epoxymurin B Epoxymurin-A F-9775A F-9775B fostriecin fujikurin D Gardnerilin A gibepyrone A Giganin gigantetronenin gigantrionenin glyflavanone A heptaketide hexaketide hydroxyclavatol hydroxyclavatol ethyl ether hydroxyclavatol methyl ether hypothemycin ikarugamycin ilicicolin Isoannoreticuin jawsamycin julichrome Q6 julichrome Q6-6 lavendiol legioliulin lehualide E lehualide F lehualide G lehualide H lehualide I lehualide J lehualide K levesquamide lovastatin luminmycin A macrolide manumycin A Marqualide Methyl 2-ethyl-4-(5-hydroxy-4,5-dimethyl-2-oxooxolan-3-yl)-2-methyl-3-oxobutanoate Methyl 2-ethyl-4-[(3R,4R,5S)-5-hydroxy-4,5-dimethyl-2-oxooxolan-3-yl]-2-methyl-3-oxobutanoate methyl nogalonate mevastatin mevinic acid mevinolinic acid Minutellin A Minutellin C Minutellin D ML-236C monacolin J monacolin J acid monacolin L monacolin L acid Monaphilol A monascin monascorubrin Monascuspurpurone Montecristin Mosin C Mosinone A Mucocin Muricatenol Muricatin C Muricin A Muricin D Muricin E Muricin F Muricin G Muricin H Murisolin myceliothermophin E nectriapyrones Neoannonin B neopikromycin Neoreticulatacin A neosartoricin nogalamycin nogalaviketone nogalonic acid nonaketide norsolorinic acid norsolorinic acid anthrone octaketide olivetolic acid pacificanone A pacificanone B Panatellin Parviflorin pederin penilactone A penilactone B(1-) penilactone D(2-) peniphenone D(1-) pentaketide phomalevone A phomalevone B phomalevone C Pitholide A Pitholide B Pitholide C Pitholide D plakortide F free acid pradimicin B pradimicin C pravastatin lactone proansamycin X protoasukamycin Purpureacin-1 Purpurenin purpurquinone A purpurquinone B purpurquinone C pyoluteorin Reticulacinone Reticulatain 2 Reticulatamol rifamycin-undecaketide carboxylic acid Rollidecin D Rollimusin Rollinecin A rubrofusarin rubrofusarin B Sabadelin salinipyrone A salinipyrone B Salinomycin sennosides Sequoiamonascin D Sequoiatone A soppiline B soppiline C spectinabilin Squamocin Squamocin B Squamocin K Squamocin L Squamolinone Squamone Squamosinin A squamostatin-A squamostatin-D Squamosten A Squamotacin Squamoxinone streptazone E tetracenomycin tetracyclines toralactone tricholignan A trihazone D(1-) trilobacin troleandomycin uvaretin Uvaricin uvarigrandin A virensol A virensol D viridicatumtoxin visnagin Water-soluble monascus pigment 7 Xanthomonasin B zaragozic acid A zaragozic acid A derivative zaragozic acid C Show first 5 Terms
inverse has_functional_parent: meroterpenoid myriaporone 3

meroterpenoid myriaporone 3 Show first 5 Terms

Phenotype

Phenotype resulting from polyketide

Phenotype where environments contain polyketide

Phenotype modified by environments containing polyketide

Human Disease / Model Data

Citations