OBO ID: DOID:10652

OBO ID: DOID:10652

Citations

(65 total)

Bhattarai, P., Gunasekaran, T.I., Belloy, M.E., Reyes-Dumeyer, D., Jülich, D., Tayran, H., Yilmaz, E., Flaherty, D., Turgutalp, B., Sukumar, G., Alba, C., McGrath, E.M., Hupalo, D.N., Bacikova, D., Le Guen, Y., Lantigua, R., Medrano, M., Rivera, D., Recio, P., Nuriel, T., Ertekin-Taner, N., Teich, A.F., Dickson, D.W., Holley, S., Greicius, M., Dalgard, C.L., Zody, M., Mayeux, R., Kizil, C., Vardarajan, B.N. (2024) Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease. Acta Neuropathologica. 147:7070

Luo, L., Yan, T., Yang, L., Zhao, M. (2024) Aluminum chloride and D-galactose induced a zebrafish model of Alzheimer's disease with cognitive deficits and aging. Computational and structural biotechnology journal. 23:223022392230-2239

Barazzuol, L., Cieri, D., Facchinello, N., Calì, T., Washbourne, P., Argenton, F., Pizzo, P. (2023) Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer's Disease Pathogenesis. Cells. 12(3):

Cao, S., Song, Z., Rong, J., Andrikopoulos, N., Liang, X., Wang, Y., Peng, G., Ding, F., Ke, P.C. (2023) Spike Protein Fragments Promote Alzheimer's Amyloidogenesis. ACS applied materials & interfaces. 15(34):40317-40329

Chen, H., Mi, J., Li, S., Liu, Z., Yang, J., Chen, R., Wang, Y., Ban, Y., Zhou, Y., Dong, W., Sang, Z. (2023) Design, synthesis and evaluation of quinoline-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease. Journal of enzyme inhibition and medicinal chemistry. 38:21696822169682

Siddiqui, A., Abidin, S.A.Z., Shah, Z.A., Othman, I., Kumari, Y. (2023) Behavioural, genomics and proteomic approach to examine Alzheimer's disease in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 271:109636

Brinza, I., Raey, M.A.E., El-Kashak, W., Eldahshan, O.A., Hritcu, L. (2022) Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (Danio rerio) Model: Involvement of Cholinergic System and Brain Oxidative Stress. Molecules. 27(18)

Cosacak, M.I., Bhattarai, P., De Jager, P.L., Menon, V., Tosto, G., Kizil, C. (2022) Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer's Disease. Cells. 11(11)

Jarosova, R., Niyangoda, S.S., Hettiarachchi, P., Johnson, M.A. (2022) Impaired Dopamine Release and Latent Learning in Alzheimer's Disease Model Zebrafish. ACS Chemical Neuroscience. 13(19):2924-2931

Kizil, C., Sariya, S., Kim, Y.A., Rajabli, F., Martin, E., Reyes-Dumeyer, D., Vardarajan, B., Maldonado, A., Haines, J.L., Mayeux, R., Jiménez-Velázquez, I.Z., Santa-Maria, I., Tosto, G. (2022) Admixture Mapping of Alzheimer's disease in Caribbean Hispanics identifies a new locus on 22q13.1. Molecular psychiatry. 27(6):2813-2820

Lee, A.J., Raghavan, N.S., Bhattarai, P., Siddiqui, T., Sariya, S., Reyes-Dumeyer, D., Flowers, X.E., Cardoso, S.A.L., De Jager, P.L., Bennett, D.A., Schneider, J.A., Menon, V., Wang, Y., Lantigua, R.A., Medrano, M., Rivera, D., Jiménez-Velázquez, I.Z., Kukull, W.A., Brickman, A.M., Manly, J.J., Tosto, G., Kizil, C., Vardarajan, B.N., Mayeux, R. (2022) FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease. Acta Neuropathologica. 144(1):59-79

McCarthy, M.M., Hardy, M.J., Leising, S.E., LaFollette, A.M., Stewart, E.S., Cogan, A.S., Sanghal, T., Matteo, K., Reeck, J.C., Oxford, J.T., Rohn, T.T. (2022) An amino-terminal fragment of apolipoprotein E4 leads to behavioral deficits, increased PHF-1 immunoreactivity, and mortality in zebrafish. PLoS One. 17:e0271707e0271707

Miao, S., He, Q., Li, C., Wu, Y., Liu, M., Chen, Y., Qi, S., Gong, K. (2022) Aaptamine - a dual acetyl - and butyrylcholinesterase inhibitor as potential anti-Alzheimer's disease agent. Pharmaceutical biology. 60:1502-1510

Patta, P.C., de Oliveira, E.M.N., de Goulart, A.C.F., Zaluski, A.B., Papaléo, R.M., Vianna, M.R.M. (2022) Amyloid-β₄₂ oligomeric forms: AFM nanoscale structural characterization and impact on long-term memory of young and aged zebrafish. Neuroscience. 497:271-281

Pecio, Ł., Kozachok, S., Brinza, I., Boiangiu, R.S., Hritcu, L., Mircea, C., Burlec, A.F., Cioanca, O., Hancianu, M., Wronikowska-Denysiuk, O., Skalicka-Woźniak, K., Oleszek, W. (2022) Neuroprotective Effect of Yucca schidigera Roezl ex Ortgies Bark Phenolic Fractions, Yuccaol B and Gloriosaol A on Scopolamine-Induced Memory Deficits in Zebrafish. Molecules. 27(12)

Sun, C., Zhang, S., Ba, S., Dang, J., Ren, Q., Zhu, Y., Liu, K., Jin, M. (2022) Eucommia ulmoides Olive Male Flower Extracts Ameliorate Alzheimer's Disease-Like Pathology in Zebrafish via Regulating Autophagy, Acetylcholinesterase, and the Dopamine Transporter. Frontiers in molecular neuroscience. 15:901953

Turgutalp, B., Bhattarai, P., Ercetin, T., Luise, C., Reis, R., Gurdal, E.E., Isaak, A., Biriken, D., Dinter, E., Sipahi, H., Schepmann, D., Junker, A., Wünsch, B., Sippl, W., Gulcan, H.O., Kizil, C., Yarim, M. (2022) Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer's Disease. Journal of medicinal chemistry. 65(18):12292-12318

Zhou, Y., Kandel, N., Bartoli, M., Serafim, L.F., ElMetwally, A.E., Falkenberg, S.M., Paredes, X.E., Nelson, C.J., Smith, N., Padovano, E., Zhang, W., Mintz, K.J., Ferreira, B.C.L.B., Cilingir, E.K., Chen, J., Shah, S.K., Prabhakar, R., Tagliaferro, A., Wang, C., Leblanc, R.M. (2022) Structure-Activity Relationship of Carbon Nitride Dots in Inhibiting Tau Aggregation. Carbon. 193:1-16

Barthelson, K., Dong, Y., Newman, M., Lardelli, M. (2021) PRESENILIN 1 Mutations Causing Early-Onset Familial Alzheimer's Disease or Familial Acne Inversa Differ in Their Effects on Genes Facilitating Energy Metabolism and Signal Transduction. Journal of Alzheimer's disease : JAD. 82(1):327-347

Barthelson, K., Newman, M., Lardelli, M. (2021) Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism. Disease models & mechanisms. 15(1):

Barthelson, K., Pederson, S.M., Newman, M., Jiang, H., Lardelli, M. (2021) In-Frame and Frameshift Mutations in Zebrafish Presenilin 2 Affect Different Cellular Functions in Young Adult Brains. Journal of Alzheimer's disease reports. 5:395-404

Cho, K.H. (2021) Structural and Functional Impairments of Reconstituted High-Density Lipoprotein by Incorporation of Recombinant β-Amyloid42. Molecules. 26(14):

Dong, Y., Newman, M., Pederson, S.M., Barthelson, K., Hin, N., Lardelli, M. (2021) Transcriptome analyses of 7-day-old zebrafish larvae possessing a familial Alzheimer's disease-like mutation in psen1 indicate effects on oxidative phosphorylation, ECM and MCM functions, and iron homeostasis. BMC Genomics. 22:211

Feng, J., Song, G., Wu, Y., Chen, X., Pang, J., Xu, Y., Shen, Q., Guo, S., Zhang, M. (2021) Plasmalogens improve swimming performance by modulating the expression of genes involved in amino acid and lipid metabolism, oxidative stress, and ferroptosis in an Alzheimer's disease zebrafish model. Food & function. 12(23):12087-12097

Lam, S., Hartmann, N., Benfeitas, R., Zhang, C., Arif, M., Turkez, H., Uhlén, M., Englert, C., Knight, R., Mardinoglu, A. (2021) Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases. Biomedicines. 9(10):

Li, Y.Q., Chen, Y., Jiang, S.Q., Shi, Y.Y., Jiang, X.L., Wu, S.S., Zhou, P., Wang, H.Y., Li, P., Li, F. (2021) An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease. Frontiers in cell and developmental biology. 9:652310

Singsai, K., Ladpala, N., Dangja, N., Boonchuen, T., Jaikhamfu, N., Fakthong, P. (2021) Effect of Streblus asper Leaf Extract on Scopolamine-Induced Memory Deficits in Zebrafish: The Model of Alzheimer's Disease. Advances in pharmacological and pharmaceutical sciences. 2021:6666726

Wang, K., Shi, J., Zhou, Y., He, Y., Mi, J., Yang, J., Liu, S., Tang, X., Liu, W., Tan, Z., Sang, Z. (2021) Design, synthesis and evaluation of cinnamic acid hybrids as multi-target-directed agents for the treatment of Alzheimer's disease. Bioorganic chemistry. 112:104879

Bhattarai, P., Cosacak, M.I., Mashkaryan, V., Demir, S., Popova, S.D., Govindarajan, N., Brandt, K., Zhang, Y., Chang, W., Ampatzis, K., Kizil, C. (2020) Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain. PLoS Biology. 18:e3000585

Brinza, I., Abd-Alkhalek, A.M., El-Raey, M.A., Boiangiu, R.S., Eldahshan, O.A., Hritcu, L. (2020) Ameliorative Effects of Rhoifolin in Scopolamine-Induced Amnesic Zebrafish (Danio rerio) Model. Antioxidants (Basel, Switzerland). 9(7):

Capatina, L., Todirascu-Ciornea, E., Napoli, E.M., Ruberto, G., Hritcu, L., Dumitru, G. (2020) Thymus vulgaris Essential Oil Protects Zebrafish against Cognitive Dysfunction by Regulating Cholinergic and Antioxidants Systems. Antioxidants (Basel, Switzerland). 9(11):

da Silva, W.M.B., Pinheiro, S.O., Alves, D.R., de Menezes, J.E.S.A., Magalhães, F.E.A., Silva, F.C.O., Marinho, M.M., Marinho, E.S., de Morais, S.M. (2020) Anacardic Acid Complexes as Possible Agents Against Alzheimer's Disease Through Their Antioxidant, In vitro, and In silico Anticholinesterase and Ansiolic Actions. Neurotoxicity research. 39(2):467-476

Giacomini, A.C., Bueno, B.W., Marcon, L., Scolari, N., Genario, R., Demin, K.A., Kolesnikova, T.O., Kalueff, A.V., de Abreu, M.S. (2020) An acetylcholinesterase inhibitor, donepezil, increases anxiety and cortisol levels in adult zebrafish. Journal of psychopharmacology (Oxford, England). 34(12):1449-1456

Hin, N., Newman, M., Kaslin, J., Douek, A.M., Lumsden, A., Nik, S.H.M., Dong, Y., Zhou, X.F., Mañucat-Tan, N.B., Ludington, A., Adelson, D.L., Pederson, S., Lardelli, M. (2020) Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. PLoS One. 15:e0227258

Javed, I., Zhang, Z., Adamcik, J., Andrikopoulos, N., Li, Y., Otzen, D.E., Lin, S., Mezzenga, R., Davis, T.P., Ding, F., Ke, P.C. (2020) Accelerated Amyloid Beta Pathogenesis by Bacterial Amyloid FapC. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 7:2001299

Lim, C.H., Kaur, P., Teo, E., Lam, V.Y.M., Zhu, F., Kibat, C., Gruber, J., Mathuru, A.S., Tolwinski, N.S. (2020) Application of optogenetic Amyloid-β distinguishes between metabolic and physical damages in neurodegeneration. eLIFE. 9:

Sang, Z., Wang, K., Bai, P., Wu, A., Shi, J., Liu, W., Zhu, G., Wang, Y., Lan, Y., Chen, Z., Zhao, Y., Qiao, Z., Wang, C., Tan, Z. (2020) Design, synthesis and biological evaluation of novel O-carbamoyl ferulamide derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 194:112265

Sang, Z., Wang, K., Shi, J., Liu, W., Cheng, X., Zhu, G., Wang, Y., Zhao, Y., Qiao, Z., Wu, A., Tan, Z. (2020) The development of advanced structural framework as multi-target-directed ligands for the treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 192:112180

Özcan, G.G., Lim, S., Leighton, P., Allison, W.T., Rihel, J. (2020) Sleep is bi-directionally modified by amyloid beta oligomers. eLIFE. 9:

Cosacak, M.I., Bhattarai, P., Reinhardt, S., Petzold, A., Dahl, A., Zhang, Y., Kizil, C. (2019) Single-Cell Transcriptomics Analyses of Neural Stem Cell Heterogeneity and Contextual Plasticity in a Zebrafish Brain Model of Amyloid Toxicity. Cell Reports. 27:1307-1318.e3

Newman, M., Hin, N., Pederson, S., Lardelli, M. (2019) Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Molecular brain. 12:43

Reinhardt, L., Kordes, S., Reinhardt, P., Glatza, M., Baumann, M., Drexler, H.C.A., Menninger, S., Zischinsky, G., Eickhoff, J., Fröb, C., Bhattarai, P., Arulmozhivarman, G., Marrone, L., Janosch, A., Adachi, K., Stehling, M., Anderson, E.N., Abo-Rady, M., Bickle, M., Pandey, U.B., Reimer, M.M., Kizil, C., Schöler, H.R., Nussbaumer, P., Klebl, B., Sterneckert, J.L. (2019) Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo. Stem Cell Reports. 12(3):502-517

Yang, J., Zhang, P., Hu, Y., Liu, T., Sun, J., Wang, X. (2019) Synthesis and biological evaluation of 3-arylcoumarins as potential anti-Alzheimer's disease agents. Journal of enzyme inhibition and medicinal chemistry. 34:651-656

Koehler, D., Shah, Z.A., Hensley, K., Williams, F.E. (2018) Lanthionine ketimine-5-ethyl ester provides neuroprotection in a zebrafish model of okadaic acid-induced Alzheimer's disease. Neurochemistry international. 115:61-68

Koehler, D., Shah, Z.A., Williams, F.E. (2018) The GSK3β inhibitor, TDZD-8, rescues cognition in a zebrafish model of okadaic acid-induced Alzheimer's disease. Neurochemistry international. 122:31-37

Sang, Z., Wang, K., Xue, H., Cao, M., Tan, Z., Liu, W. (2018) Design, synthesis and evaluation of novel ferulic acid derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease. ACS Chemical Neuroscience. 10(2):1008-1024

Bhattarai, P., Thomas, A.K., Cosacak, M.I., Papadimitriou, C., Mashkaryan, V., Zhang, Y., Kizil, C. (2017) Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain. Journal of visualized experiments : JoVE. (128)

Bhattarai, P., Thomas, A.K., Zhang, Y., Kizil, C. (2017) The effects of aging on Amyloid-β42-induced neurodegeneration and regeneration in adult zebrafish brain. Neurogenesis (Austin, Tex.). 4:e1322666

Cosacak, M.I., Bhattarai, P., Bocova, L., Dzewas, T., Mashkaryan, V., Papadimitriou, C., Brandt, K., Hollak, H., Antos, C.L., Kizil, C. (2017) Human TAU^P301L overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain.. Scientific Reports. 7:12959

Köglsberger, S., Cordero-Maldonado, M.L., Antony, P., Forster, J.I., Garcia, P., Buttini, M., Crawford, A., Glaab, E. (2017) Gender-Specific Expression of Ubiquitin-Specific Peptidase 9 Modulates Tau Expression and Phosphorylation: Possible Implications for Tauopathies. Molecular neurobiology. 54(10):7979-7993

Lee, J., Peterson, S.M., Freeman, J.L. (2017) Sex-specific characterization and evaluation of the Alzheimer's disease genetic risk factor sorl1 in zebrafish during aging and in the adult brain following a 100 ppb embryonic lead exposure. Journal of applied toxicology : JAT. 37(4):400-407

Newman, M., Halter, L., Lim, A., Lardelli, M. (2017) Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease. PLoS One. 12:e0179859

Wang, B.J., Her, G.M., Hu, M.K., Chen, Y.W., Tung, Y.T., Wu, P.Y., Hsu, W.M., Lee, H., Jin, L.W., Hwang, S.L., Chen, R.P., Huang, C.J., Liao, Y.F. (2017) ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 114(15):E3129-E3138

Bhattarai, P., Thomas, A.K., Cosacak, M.I., Papadimitriou, C., Mashkaryan, V., Froc, C., Reinhardt, S., Kurth, T., Dahl, A., Zhang, Y., Kizil, C. (2016) IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain. Cell Reports. 17:941-948

Ebrahimie, E., Moussavi-Nik, S.H., Newman, M., Van Der Hoek, M., Lardelli, M. (2016) The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress. Journal of Alzheimer's disease : JAD. 52(2):581-608

Lee, J., Freeman, J.L. (2016) Embryonic exposure to 10 μg L(-1) lead results in female-specific expression changes in genes associated with nervous system development and function and Alzheimer's disease in aged adult zebrafish brain. Metallomics : integrated biometal science. 8(6):589-96

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Sepulveda-Diaz, J.E., Alavi Naini, S.M., Huynh, M.B., Ouidja, M.O., Yanicostas, C., Chantepie, S., Villares, J., Lamari, F., Jospin, E., van Kuppevelt, T.H., Mensah-Nyagan, A.G., Raisman-Vozari, R., Soussi-Yanicostas, N., Papy-Garcia, D. (2015) HS3ST2 expression is critical for the abnormal phosphorylation of tau in Alzheimer's disease-related tau pathology. Brain : a journal of neurology. 138(Pt 5):1339-54

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