Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990603-12
Gene Name: wingless-type MMTV integration site family, member 11
Gene Symbol: wnt11
Previous Names: cb748 (1), silberblick, slb
Nomenclature History
GENE EXPRESSION
All Expression Data: 37 figures from 23 publications
Directly Submitted Expression Data: 7 figures (64 images) from Thisse et al., 2001 [cb748]
  6 figures (16 images) from Thisse et al., 2005 [eu266]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  adaxial cell, EVL, forerunner cell group, head mesenchyme (all 27) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 23 genotypes
Alleles: tx226, tz216, u148, wnt11_unspecified
Knockdown reagents: MO1-wnt11 (1), MO2-wnt11 (1), MO3-wnt11 (1)
PHENOTYPE
Data: 40 figures from 27 publications
Observed in: anterior neural plate, axial chorda mesoderm, axial hypoblast, axial mesoderm (all 42) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process Kupffer's vesicle development (more)
Cellular Component plasma membrane (more)
Molecular Function Ras GTPase activator activity (more)
GO Terms (all 54)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wnt11-001 (1) 2132
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt11 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    wnt11 Contained in: [BAC] CH73-223D24 (1) (order this)
    wnt11 Contains: [SNP] rs3727880 (1)
    wnt11 Encodes: [EST] cb748 (1), eu266 (1)
    [cDNA] MGC:193977 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001144804 (1) 2132 bp
    Genomic GenBank:CU571324 (1) 78830 bp
    Select Tool
    Polypeptide UniProtKB:O73864 (1) 354 aa
    Sequence Clusters UniGene:75830 (1)
    Sequence Information (all 16)
    OTHER wnt11 GENE PAGES
  • Gene:791595 (1)
  • VEGA:OTTDARG00000029156 (1)
  • Ensembl(Zv9):ENSDARG00000004256 (1)
  • MAPPING INFORMATION
    Chr: 5 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish wnt11 5  
    Human WNT11 11 (11q13.5)
  • OMIM:603699
  • Gene:7481
  • Mouse Wnt11 7 ( 53.90)
  • MGI:101948
  • Gene:22411
  • CITATIONS (123)