ZFIN ID: ZDB-GENE-990415-198
Gene Name: teratocarcinoma-derived growth factor 1
Gene Symbol: tdgf1
Previous Names: cb85 (1), cripto, oep, one eyed pinhead, one-eyed pinhead, wu:fe01d04, zgc:109829
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 24 figures from 16 publications
Directly Submitted Expression Data: 6 figures (38 images) from Thisse et al., 2001 [cb85]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Pharyngula:Prim-25 (36.0h-42.0h)
  axis, blastomere, diencephalon, epiphysis (all 20) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017432Tg Transgenic Insertion Unknown Unknown DNA
m134 Point Mutation Unknown Premature Stop ENU
tdgf1_unspecified Unspecified Unknown Unknown
tz257 Point Mutation Start Codon Start Loss ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • z1 Deficiency Unknown Unknown G_RAYS
    Targeting reagents: MO1-tdgf1 (2)
    PHENOTYPE
    Data: 51 figures from 32 publications
    Observed in: anatomical system, anterior axial hypoblast, axis, brain (all 82) expand
    DISEASE ASSOCIATED WITH tdgf1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Forebrain defects
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process floor plate formation (more)
    Cellular Component external side of plasma membrane (more)
    GO Terms (all 31)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013032 (1)
  • InterPro:IPR019011 (1)
  • PROSITE:PS00022 (1)
  • Pfam:PF09443 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tdgf1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tdgf1Encodes: [EST] cb85 (1) (order this), fe01d04
    [cDNA] MGC:109829 (1) (order this), MGC:173598 (1) (order this), MGC:174150 (1) (order this), MGC:192394 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001328408 (1) 1800bp
    Genomic GenBank:CABZ01070743 (1) 6287bp
    Polypeptide UniProtKB:F1Q691 (1) 190aa
    Sequence Clusters UniGene:52009 (1)
    Sequence Information (all 37)
    OTHER tdgf1 GENE PAGES
  • Gene:30304 (1)
  • Ensembl(GRCz10):ENSDARG00000035095 (1)
  • ORTHOLOGY for tdgf1 (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human TDGF1 3
  • Gene:6997
  • OMIM:187395
  • HGNC:11701
  • Amino acid sequence comparison (2)
    Mouse Tdgf1 9
  • MGI:98658
  • Gene:21667
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (246)