Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-198
Gene Name: teratocarcinoma-derived growth factor 1
Gene Symbol: tdgf1
Previous Names: cb85 (1), cripto, oep, one eyed pinhead, one-eyed pinhead, wu:fe01d04, zgc:109829
Location: Chr: 10   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 24 figures from 16 publications
Directly Submitted Expression Data: 6 figures (38 images) from Thisse et al., 2001 [cb85]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Pharyngula:Prim-25 (36.0h-42.0h)
  axis, blastomere, diencephalon, epiphysis (all 18) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 34 genotypes
Alleles: b173, la017432Tg, m134, st2, tdgf1_unspecified (all 7) expand
Knockdown reagents: MO1-tdgf1 (2)
PHENOTYPE
Data: 33 figures from 22 publications
Observed in: anatomical system, anterior axial hypoblast, axis, brain (all 60) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Forebrain defects
GENE ONTOLOGY
Ontology GO Term
Biological Process mesendoderm development (more)
Cellular Component external side of plasma membrane (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013032 (1)
  • InterPro:IPR019011 (1)
  • PROSITE:PS00022 (1)
  • Pfam:PF09443 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM tdgf1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tdgf1 Encodes: [EST] cb85 (1) (order this), fe01d04
    [cDNA] MGC:109829 (1) (order this), MGC:173598 (1) (order this), MGC:174150 (1) (order this), MGC:192394 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131092 (1) 1535 bp
    Genomic GenBank:CABZ01070743 (1) 6287 bp
    Polypeptide UniProtKB:F1Q691 (1) 190 aa
    Sequence Clusters UniGene:52009 (1)
    Sequence Information (all 35)
    OTHER tdgf1 GENE PAGES
  • Gene:30304 (1)
  • Ensembl(Zv9):ENSDARG00000035095 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish tdgf1 10  
    Human TDGF1 3 (3p21.31)
  • OMIM:187395
  • Gene:6997
  • Mouse Tdgf1 9 ( 60.79 cM)
  • MGI:98658
  • Gene:21667
  • Orthology Details
    CITATIONS (222)