Gene
lfng
- ID
- ZDB-GENE-980605-16
- Name
- LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Symbol
- lfng Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Involved in fin regeneration; hypochord development; and negative regulation of neuron differentiation. Predicted to localize to integral component of Golgi membrane. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Is expressed in several structures, including blastodisc; central nervous system; germ ring; neural plate; and sensory system. Orthologous to human LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 28 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55213 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Nikolaou et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spondylocostal dysostosis 3 | Alliance | Spondylocostal dysostosis 3, autosomal recessive | 609813 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fringe | Fringe-like, glycosyltransferase domain |
|---|---|---|---|
|
UniProtKB:B2GQK5
|
374 | ||
|
UniProtKB:Q8JHF2
|
374 |
Interactions and Pathways
No data available
Plasmids
No data available