Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-87
Gene Name: wingless-type MMTV integration site family, member 5b
Gene Symbol: wnt5b
Previous Names: ppt, wnt5, wnt5a, wnt[b] (1), ZfWnt5 (2), Zwnt[b] (1), CHUNP6928, id:ibd5111, pipe tail, pipetail (1), wu:fk85g06
Nomenclature History
GENE EXPRESSION
All Expression Data: 32 figures from 22 publications
Directly Submitted Expression Data: 3 figures (3 images) from Kudoh et al., 2001 [ibd5111]
  6 figures (17 images) from Thisse et al., 2005 [eu891]
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Hatching:Long-pec (48.0h-60.0h)
  axial mesoderm, dorsal fin, germ ring, head mesenchyme (all 19) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 28 genotypes
Alleles: hi1780bTg, hi2735bTg, la015530Tg, la024747Tg, la029041Tg (all 12) expand
Knockdown reagents: MO1-wnt5b (1), MO2-wnt5b (1), MO3-wnt5b (1), MO4-wnt5b (1)
PHENOTYPE
Data: 52 figures from 24 publications
Observed in: angiogenesis, anterior cerebral vein, anterior neural plate, asymmetric protein localization (all 61) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process Wnt receptor signaling pathway, calcium modulating pathway (more)
Cellular Component extracellular region (more)
Molecular Function receptor binding (more)
GO Terms (all 29)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR018161 (1)
  • InterPro:IPR026537 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wnt5b-003 (1) 4450
    Select Tool
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt5b
    Tg(hsp70l:wnt5b-GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    wnt5b Contained in: [BAC] CH73-211C7 (1) (order this), CH211-281K12 (1) (order this), DKEY-85M15 (1) (order this)
    wnt5b Encodes: [EST] eu891 (1), fk85g06, ibd5111 (1) (order this)
    [STS] chunp6928
    [cDNA] MGC:194419 (1) (order this), MGC:194422 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130937 (1) 1730 bp
    Select Tool
    Genomic GenBank:BX649324 (1) 218137 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QBD2 (1) 380 aa
    Select Tool
    Sequence Clusters UniGene:389 (1)
    Sequence Information (all 25)
    OTHER wnt5b GENE PAGES
  • Gene:30105 (1)
  • VEGA:OTTDARG00000023607 (1)
  • Ensembl(Zv9):ENSDARG00000034894 (1)
    • MAPPING INFORMATION
    Chr: 4 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish wnt5b 4  
    Fruit fly Wnt5 X
  • FLYBASE:FBgn0010194
  • Gene:32838
    • Human WNT5B 12 (12p13.3)
  • OMIM:606361
  • Gene:81029
    • Mouse Wnt5b 6 ( 56.86)
  • MGI:98959
  • Gene:22419
    • Orthology Details
    CITATIONS (100)