ZFIN ID: ZDB-GENE-980526-488
Gene Name: fibroblast growth factor receptor 4
Gene Symbol: fgfr4
Previous Names: etID309818.21 (1), wu:fc13h10 (1), zgc:111935
Location: Chr: 21   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 24 figures from 22 publications
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
  brain, caudal vein plexus, cephalic musculature, choroidal fissure (all 38) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
hu3514 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hu3582 Unknown ENU
    la022005Tg Transgenic Insertion DNA
    sa24004 Point Mutation ENU
    sa24005 Point Mutation ENU
    Targeting reagents: MO1-fgfr4 (1), MO2-fgfr4 (1)
    PHENOTYPE
    Data: Fig. 10 from Nakayama et al., 2008
    Observed in: optic cup, solid lens vesicle
    DISEASE ASSOCIATED WITH fgfr4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Cancer progression/metastasis}
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fibroblast growth factor receptor signaling pathway (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function protein binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR003598 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013151 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016248 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020635 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF00047 (1)
  • Pfam:PF07679 (1)
  • Pfam:PF07714 (1)
  • EC:2.7.10.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fgfr4-001 (1) 5011
    ncRNA fgfr4-002 (1) 3229
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fgfr4 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    fgfr4 Contained in: [BAC] CH211-281E1 (1) (order this), DKEY-53B2 (1) (order this)
    fgfr4 Contains: [BAC END] zc120k11.ya (1)
    fgfr4 Encodes: [EST] fc13h10 (1)
    [cDNA] cssl:d109 (1), MGC:198431 (1) (order this)
    fgfr4 Has Artifact: [cDNA] MGC:111935 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131430 (1) 4705 bp
    Genomic GenBank:BX649250 (1) 165729 bp
    Select Tool
    Polypeptide UniProtKB:B7ZVT9 (1) 922 aa
    Sequence Clusters UniGene:75058 (1)
    Sequence Information (all 22)
    OTHER fgfr4 GENE PAGES
  • Gene:100000160 (1)
  • VEGA:OTTDARG00000021085 (1)
  • Ensembl(Zv9):ENSDARG00000069105 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish fgfr4 21  
    Human FGFR4 5 (5q35.2)
  • OMIM:134935
  • Gene:2264
  • Mouse Fgfr4 13 ( 29.80 cM)
  • MGI:95525
  • Gene:14186
  • Orthology Details
    CITATIONS (75)