ZFIN Gene: fgfr4

ZFIN ID: ZDB-GENE-980526-488

ZFIN ID: ZDB-GENE-980526-488

Gene Name:	fibroblast growth factor receptor 4
Gene Symbol:	fgfr4
Previous Names:	etID309818.21 (1), wu:fc13h10 (1), zgc:111935
Nomenclature History

GENE EXPRESSION
All Expression Data:	15 figures from 14 publications
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
	brain , diencephalon , heart , midbrain (all 14)
Curated Microarray Expression:	GEO (1)

MUTANTS AND TARGETED KNOCKDOWNS

PHENOTYPE

Data:	Fig. 10 from Nakayama et al., 2008
Observed in:	optic cup , solid lens vesicle

Phenotype of Human Orthologue	OMIM Phenotype ID
{Cancer progression/metastasis}

GENE ONTOLOGY

Ontology	GO Term
Biological Process	fibroblast growth factor receptor signaling pathway (more)
Cellular Component	endoplasmic reticulum (more)
Molecular Function	protein binding (more)

GO Terms (all 19)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000719 (1) InterPro:IPR001245 (1) InterPro:IPR003598 (1) InterPro:IPR007110 (1) InterPro:IPR008266 (1) InterPro:IPR011009 (1) InterPro:IPR013098 (1) InterPro:IPR013151 (1) InterPro:IPR013783 (1) InterPro:IPR016248 (1) InterPro:IPR017441 (1) InterPro:IPR020635 (1)	PROSITE:PS00107 (1) PROSITE:PS00109 (1) PROSITE:PS50011 (1) PROSITE:PS50835 (1)	Pfam:PF00047 (1) Pfam:PF07679 (1) Pfam:PF07714 (1)	EC:2.7.10.1 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	fgfr4-001 (1)	5011	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
ncRNA	fgfr4-002 (1)	3229	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

GENE PRODUCT DESCRIPTION

ANTIBODIES No data available

CONSTRUCTS WITH SEQUENCES FROM fgfr4 No data available

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

fgfr4 Contained in:	[BAC] CH211-281E1 (1) (order this), DKEY-53B2 (1) (order this)
fgfr4 Contains:	[BAC END] zc120k11.ya (1)
fgfr4 Encodes:	[EST] fc13h10 (1) [cDNA] cssl:d109 (1), MGC:198431 (1) (order this)
fgfr4 Has Artifact:	[cDNA] MGC:111935 (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131430 (1)	4705 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:BX649250 (1)	165729 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q90413 (1)	922 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:75058 (1)

OTHER fgfr4 GENE PAGES

Gene:100000160 (1)

VEGA:OTTDARG00000021085 (1)

Ensembl(Zv9):ENSDARG00000069105 (1)

MAPPING INFORMATION
Chr: 21 Details	View Map: Merged Individual Panels

ORTHOLOGY

CITATIONS (62)