Gene

rxrga

ID

ZDB-GENE-980526-36

Name

retinoid x receptor, gamma a

Symbol

rxrga Nomenclature History

Previous Names

rxra (1)
rxrg
NR2B3 (1)
nr2b3a (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Exhibits nuclear receptor activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription factor complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is expressed in several structures, including mesoderm; neural rod; pharyngeal arch; retina; and tail bud. Orthologous to human RXRG (retinoid X receptor gamma).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

32 figures from 11 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:73235 (12 images)
u29940 (38 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rxrga Human Ortholog

No data available

Associated With rxrga Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Domain	IPR021780	Nuclear/hormone receptor activator site AF-1
Family	IPR000003	Retinoid X receptor/HNF4
Family	IPR001723	Nuclear hormone receptor
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily

Domain Details Per Protein

Protein	Length	Nuclear hormone receptor	Nuclear/hormone receptor activator site AF-1	Nuclear hormone receptor, ligand-binding domain	Nuclear hormone receptor-like domain superfamily	Retinoid X receptor/HNF4	Zinc finger, NHR/GATA-type	Zinc finger, nuclear hormone receptor-type
UniProtKB:A0A8N1TSS1 InterPro	441
UniProtKB:Q90416 InterPro	441

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
ncRNA	rxrga-001 (1) Ensembl	Havana	99 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

SignaFish

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations