ZFIN ID: ZDB-GENE-980526-280
Gene Name: distal-less homeobox 3b
Gene Symbol: dlx3b

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Previous Names: dlx-3, dlx3, id:ibd3531 (1), wu:fb83f11, zgc:91827

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 226 figures from 150 publications
Directly Submitted Expression Data: 6 figures (36 images) from Thisse et al., 2005 [eu221]
  5 figures (8 images) from Kudoh et al., 2001 [ibd3531]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Days 14-20 (14d-21d, 6.2mm, 10 teeth)
  anatomical structure, anguloarticular, anterior neural plate, branchiostegal membrane (all 78) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa94 Point Mutation Unknown Nonsynonymous ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa22023 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-dlx3b, MO2-dlx3b, MO3-dlx3b, MO4-dlx3b, MO5-dlx3b (1)
    PHENOTYPE
    Data: 4 figures from 3 publications
    Observed in: mandibular arch skeleton joint, olfactory placode development, otic vesicle, otic vesicle development (all 5) expand
    DISEASE ASSOCIATED WITH dlx3b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    amelogenesis imperfecta type 4 Amelogenesis imperfecta, type IV 104510
    Trichodontoosseous syndrome 190320
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process auditory receptor cell fate specification (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • InterPro:IPR022135 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF12413 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dlx3b-001 (1) 1591
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dlx3b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    dlx3bContained in: [BAC] CH73-209K3 (1) (order this)
    dlx3bEncodes: [EST] eu221 (1), fb83f11, ibd3531 (1) (order this)
    [cDNA] MGC:91827 (1) (order this), MGC:191167 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131322 (1) 1593bp
    Genomic GenBank:CU468219 (1) 126695bp
    Select Tool
    Polypeptide UniProtKB:Q01702 (1) 269aa
    Sequence Clusters UniGene:77568 (1)
    Sequence Information (all 18)
    OTHER dlx3b GENE PAGES
  • Gene:30585 (1)
  • VEGA:OTTDARG00000035619 (1)
  • Ensembl(GRCz10):ENSDARG00000014626 (1)
  • ORTHOLOGY for dlx3b (Chr: 12)
    Species Symbol Chromosome Accession # Evidence
    Human DLX3 17
  • Gene:1747
  • OMIM:600525
  • HGNC:2916
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (4)
    Mouse Dlx3 11
  • MGI:94903
  • Gene:13393
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (286)