ZFIN ID: ZDB-GENE-980526-235
Gene Name: twist2
Gene Symbol: twist2
Previous Names: dermo1, zgc:101904 (1)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 26 figures from 12 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2004 [MGC:101904]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  artery, axial chorda mesoderm, axial mesoderm, axial vasculature (all 25) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-twist2 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH twist2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Focal facial dermal dysplasia 3, Setleis type 227260
Barber-Say syndrome 209885
Ablepharon-macrostomia syndrome 200110
GENE ONTOLOGY
Ontology GO Term
Molecular Function protein dimerization activity (more)
GO Terms (all 1)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA twist2-001 (1) 1227
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM twist2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    twist2Contained in: [BAC] CH73-282H7 (1) (order this)
    twist2Encodes: [cDNA] MGC:101904 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001005956 (1) 1051bp
    Genomic GenBank:CU929427 (1) 58358bp
    Select Tool
    Polypeptide UniProtKB:Q5XJI8 (1) 163aa
    Sequence Clusters UniGene:36752 (1)
    Sequence Information (all 11)
    OTHER twist2 GENE PAGES
  • Gene:30395 (1)
  • VEGA:OTTDARG00000032844 (1)
  • Ensembl(GRCz10):ENSDARG00000078266 (1)
  • ORTHOLOGY for twist2 (Chr: 9)
    Species Symbol Chromosome Accession # Evidence
    Human TWIST2 2
  • Gene:117581
  • OMIM:607556
  • HGNC:20670
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (3)
    Mouse Twist2 1
  • MGI:104685
  • Gene:13345
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (34)