ZFIN ID: ZDB-GENE-980526-235
Gene Name: twist2
Gene Symbol: twist2
Previous Names: dermo1, zgc:101904 (1)
Location: Chr: 9 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 26 figures from 12 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2004 [MGC:101904]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  artery, axial chorda mesoderm, axial mesoderm, axial vasculature (all 25) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-twist2 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH twist2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Focal facial dermal dysplasia 3, Setleis type 227260
Barber-Say syndrome 209885
Ablepharon-macrostomia syndrome 200110
GENE ONTOLOGY
Ontology GO Term
Molecular Function protein dimerization activity (more)
GO Terms (all 1)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA twist2-001 (1) 1227
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM twist2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    twist2Contained in: [BAC] CH73-282H7 (1) (order this)
    twist2Encodes: [cDNA] MGC:101904 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001005956 (1) 1051bp
    Genomic GenBank:CU929427 (1) 58358bp
    Select Tool
    Polypeptide UniProtKB:Q5XJI8 (1) 163aa
    Sequence Clusters UniGene:36752 (1)
    Sequence Information (all 11)
    OTHER twist2 GENE PAGES
  • Gene:30395 (1)
  • VEGA:OTTDARG00000032844 (1)
  • Ensembl(GRCz10):ENSDARG00000078266 (1)
  • ORTHOLOGY for twist2 (Chr: 9)
    Species Symbol Chromosome Accession # Evidence
    Human TWIST2 2
  • Gene:117581
  • OMIM:607556
  • HGNC:20670
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (3)
    Mouse Twist2 1
  • MGI:104685
  • Gene:13345
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (34)