Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-235
Gene Name: twist2
Gene Symbol: twist2
Previous Names: dermo1, zgc:101904 (1)
Location: Chr: 9   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 26 figures from 12 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2004 [MGC:101904]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  artery, axial chorda mesoderm, axial mesoderm, axial vasculature (all 25) expand
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-twist2 (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Focal facial dermal dysplasia 3, Setleis type 227260
GENE ONTOLOGY
Ontology GO Term
Molecular Function protein dimerization activity (more)
GO Terms (all 1)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA twist2-001 (1) 1227
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM twist2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    twist2 Contained in: [BAC] CH73-282H7 (1) (order this)
    twist2 Encodes: [cDNA] MGC:101904 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001005956 (1) 1051 bp
    Genomic GenBank:CU929427 (1) 58358 bp
    Select Tool
    Polypeptide UniProtKB:Q5XJI8 (1) 163 aa
    Sequence Clusters UniGene:36752 (1)
    Sequence Information (all 11)
    OTHER twist2 GENE PAGES
  • Gene:30395 (1)
  • VEGA:OTTDARG00000032844 (1)
  • Ensembl(Zv9):ENSDARG00000078266 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish twist2 9  
    Human TWIST2 2 (2q37.3)
  • OMIM:607556
  • Gene:117581
  • Mouse Twist2 1 ( 46.24 cM)
  • MGI:104685
  • Gene:13345
  • Orthology Details
    CITATIONS (33)