Gene
cecr2
- ID
- ZDB-GENE-131121-533
- Name
- CECR2 histone acetyl-lysine reader
- Symbol
- cecr2 Nomenclature History
- Previous Names
-
- si:ch211-276c7.3
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be part of CERF complex. Orthologous to human CECR2 (CECR2 histone acetyl-lysine reader).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Targeting Reagent | Created Alleles | Citations |
---|---|---|
CRISPR1-cecr2 | Brocal et al., 2016 | |
CRISPR2-cecr2 | Brocal et al., 2016 | |
MO1-cecr2 | N/A | Huang et al., 2013 |
MO2-cecr2 | N/A | Huang et al., 2013 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Bromodomain | Bromodomain, conserved site | Bromodomain-like superfamily | Chromatin remodeling regulator CECR2 |
---|---|---|---|---|---|
UniProtKB:A0A8M1RL92
|
1501 | ||||
UniProtKB:F1RCN2
|
1502 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-276C7 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_002666820 (1) | |||
Genomic | GenBank:BX004976 (1) | 151137 nt | ||
Polypeptide | UniProtKB:F1RCN2 (1) | 1502 aa |
- Comparative Orthology
- Alliance
- Brocal, I., White, R.J., Dooley, C.M., Carruthers, S.N., Clark, R., Hall, A., Busch-Nentwich, E.M., Stemple, D.L., Kettleborough, R.N. (2016) Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish. BMC Genomics. 17:259
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology. 15(12):1516-1525
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