Gene
man2c1
- ID
- ZDB-GENE-101103-4
- Name
- mannosidase, alpha, class 2C, member 1
- Symbol
- man2c1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable alpha-mannosidase activity. Predicted to be involved in oligosaccharide catabolic process. Predicted to act upstream of or within mannose metabolic process. Human ortholog(s) of this gene implicated in congenital disorder of deglycosylation 2. Orthologous to human MAN2C1 (mannosidase alpha class 2C member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of deglycosylation 2 | Alliance | Congenital disorder of deglycosylation 2 | 619775 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000602 | Glycoside hydrolase family 38, N-terminal domain |
| Domain | IPR011682 | Glycosyl hydrolase family 38, C-terminal |
| Domain | IPR015341 | Glycoside hydrolase family 38, central domain |
| Domain | IPR041147 | Glycosyl hydrolases family 38, C-terminal beta sandwich domain |
| Domain | IPR054723 | Alpha-mannosidase Ams1-like, N-terminal |
| Homologous_superfamily | IPR011013 | Galactose mutarotase-like domain superfamily |
| Homologous_superfamily | IPR011330 | Glycoside hydrolase/deacetylase, beta/alpha-barrel |
| Homologous_superfamily | IPR027291 | Glycoside hydrolase 38, N-terminal domain superfamily |
| Homologous_superfamily | IPR028995 | Glycoside hydrolase families 57/38, central domain superfamily |
| Homologous_superfamily | IPR037094 | Glycoside hydrolase family 38, central domain superfamily |
Domain Details Per Protein
| Protein | Length | Alpha-mannosidase Ams1-like, N-terminal | Galactose mutarotase-like domain superfamily | Glycoside hydrolase 38, N-terminal domain superfamily | Glycoside hydrolase/deacetylase, beta/alpha-barrel | Glycoside hydrolase families 57/38, central domain superfamily | Glycoside hydrolase family 38, central domain | Glycoside hydrolase family 38, central domain superfamily | Glycoside hydrolase family 38, N-terminal domain | Glycosyl hydrolase family 38, C-terminal | Glycosyl hydrolases family 38, C-terminal beta sandwich domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B7A6
|
1034 | ||||||||||
|
UniProtKB:X1WCE5
|
1024 | ||||||||||
|
UniProtKB:A0A8M6YW39
|
927 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
man2c1-201
(1)
|
Ensembl | 4,724 nt |
Interactions and Pathways
No data available
Plasmids
No data available