Gene
gucy1b1
- ID
- ZDB-GENE-090313-160
- Name
- guanylate cyclase 1 soluble subunit beta 1
- Symbol
- gucy1b1 Nomenclature History
- Previous Names
-
- gucy1b3
- si:ch73-34b5.3
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity; guanylate cyclase activity; and heme binding activity. Predicted to be involved in cGMP-mediated signaling and trans-synaptic signaling by nitric oxide, modulating synaptic transmission. Predicted to localize to presynaptic active zone. Orthologous to human GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Vishnolia et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018297 | Adenylyl cyclase class-4/guanylyl cyclase, conserved site |
Domain | IPR001054 | Adenylyl cyclase class-3/4/guanylyl cyclase |
Domain | IPR011644 | Heme NO-binding |
Domain | IPR011645 | Haem NO binding associated |
Homologous_superfamily | IPR024096 | NO signalling/Golgi transport ligand-binding domain superfamily |
Homologous_superfamily | IPR029787 | Nucleotide cyclase |
Homologous_superfamily | IPR038158 | H-NOX domain superfamily |
Homologous_superfamily | IPR042463 | Haem NO binding associated domain superfamily |
Domain Details Per Protein
Protein | Length | Adenylyl cyclase class-3/4/guanylyl cyclase | Adenylyl cyclase class-4/guanylyl cyclase, conserved site | Haem NO binding associated | Haem NO binding associated domain superfamily | Heme NO-binding | H-NOX domain superfamily | NO signalling/Golgi transport ligand-binding domain superfamily | Nucleotide cyclase |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1QNR4
|
608 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
gucy1b1-201
(1)
|
Ensembl | 2,122 nt | ||
ncRNA |
gucy1b3-002
(1)
|
Ensembl | 699 nt |
Interactions and Pathways
No data available
Plasmids
No data available