Gene
si:dkey-26i13.8
- ID
- ZDB-GENE-090312-134
- Name
- si:dkey-26i13.8
- Symbol
- si:dkey-26i13.8 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and cytoskeletal motor activity. Acts upstream of or within cilium assembly. Located in motile cilium.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Choksi et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Choksi et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa15225 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa18615 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa39563 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
zko246a | Allele with one deletion | Unknown | Unknown | CRISPR |
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Targeting Reagent | Created Alleles | Citations |
---|---|---|
CRISPR1-si:dkey-26i13.8 | (2) | |
MO1-si:dkey-26i13.8 | N/A | Choksi et al., 2014 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Kinesin-like protein | Kinesin motor domain | Kinesin motor domain superfamily | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|---|
UniProtKB:A0A8M6YYY0 | InterPro | 990 | ||||
UniProtKB:A0A8M1Q799 | InterPro | 991 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
si:dkey-26i13.8-201
(1)
|
Ensembl | 460 nt | ||
mRNA |
si:dkey-26i13.8-202
(1)
|
Ensembl | 3,125 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-26I13 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_068221007 (1) | 4968 nt | ||
Genomic | GenBank:BX569798 (1) | 215607 nt | ||
Polypeptide | UniProtKB:A0A8M1Q799 (1) | 991 aa |
No data available
- Sun, Y., Zhang, B., Luo, L., Shi, D.L., Wang, H., Cui, Z., Huang, H., Cao, Y., Shu, X., Zhang, W., Zhou, J., Li, Y., Du, J., Zhao, Q., Chen, J., Zhong, H., Zhong, T.P., Li, L., Xiong, J.W., Peng, J., Xiao, W., Zhang, J., Yao, J., Yin, Z., Mo, X., Peng, G., Zhu, J., Chen, Y., Zhou, Y., Liu, D., Pan, W., Zhang, Y., Ruan, H., Liu, F., Zhu, Z., Meng, A., ZAKOC Consortium (2019) Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome research. 30(1):118-26
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Choksi, S.P., Babu, D., Lau, D., Yu, X., Roy, S. (2014) Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Development (Cambridge, England). 141:3410-9
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