Gene
ubr2
- ID
- ZDB-GENE-081107-29
- Name
- ubiquitin protein ligase E3 component n-recognin 2
- Symbol
- ubr2 Nomenclature History
- Previous Names
-
- si:ch211-239i4.2
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in histone H2A ubiquitination and ubiquitin-dependent protein catabolic process via the N-end rule pathway. Predicted to act upstream of or within protein catabolic process. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in female organism. Orthologous to human UBR2 (ubiquitin protein ligase E3 component n-recognin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Newman et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003126 | Zinc finger, UBR-type |
| Domain | IPR003769 | Adaptor protein ClpS, core |
| Domain | IPR044046 | E3 ubiquitin-protein ligase UBR-like, C-terminal |
| Domain | IPR047508 | E3 ubiquitin-protein ligase UBR2, UBR-box |
| Family | IPR039164 | E3 ubiquitin-protein ligase UBR1-like |
| Homologous_superfamily | IPR014719 | Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR042065 | E3 ubiquitin-protein ligase ELL-like |
Domain Details Per Protein
| Protein | Length | Adaptor protein ClpS, core | E3 ubiquitin-protein ligase ELL-like | E3 ubiquitin-protein ligase UBR1-like | E3 ubiquitin-protein ligase UBR2, UBR-box | E3 ubiquitin-protein ligase UBR-like, C-terminal | Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like | Winged helix DNA-binding domain superfamily | Zinc finger, UBR-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B2U0
|
1756 | ||||||||
|
UniProtKB:A0A8M9PB10
|
946 | ||||||||
|
UniProtKB:A0A8M6Z2H4
|
1770 | ||||||||
|
UniProtKB:A0A8M2B2K6
|
1757 | ||||||||
|
UniProtKB:A0A8M9PML5
|
546 | ||||||||
|
UniProtKB:A0A8M1QLF4
|
1756 | ||||||||
|
UniProtKB:A0A8M6Z1W9
|
1771 | ||||||||
|
UniProtKB:A0A8M6Z9B0
|
1771 | ||||||||
|
UniProtKB:A0A8M6Z417
|
1371 |
Interactions and Pathways
No data available
Plasmids
No data available