Gene
hes2.1
- ID
- ZDB-GENE-081104-104
- Name
- hes family bHLH transcription factor 2, tandem duplicate 1
- Symbol
- hes2.1 Nomenclature History
- Previous Names
-
- Hes2a (1)
- si:ch211-122n14.3
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; negative regulation of transcription by RNA polymerase II; and regulation of neurogenesis. Predicted to localize to nucleus. Is expressed in eye; gill; gonad; heart; and liver. Orthologous to human HES2 (hes family bHLH transcription factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhou et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Hairy and Enhancer of Split/HEY-related | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
---|---|---|---|---|
UniProtKB:A0A8M9QIL4
|
195 | |||
UniProtKB:B0V2G6
|
150 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
hes2.1-201
(1)
|
Havana | 856 nt | |
mRNA |
hes2.1-202
(1)
|
Ensembl | 453 nt |
Interactions and Pathways
No data available
Plasmids
No data available