Gene
adrb1
- ID
- ZDB-GENE-081022-145
- Name
- adrenoceptor beta 1
- Symbol
- adrb1 Nomenclature History
- Previous Names
-
- zgc:194728
- zgc:194731
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable beta1-adrenergic receptor activity. Acts upstream of or within regulation of heart rate and venous blood vessel morphogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adipose tissue; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypertension (multiple); low tension glaucoma; obstructive sleep apnea; and periodontitis. Orthologous to human ADRB1 (adrenoceptor beta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adrenoceptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|
|
UniProtKB:B3DHM6
|
390 |
Interactions and Pathways
No data available
Plasmids
No data available