Gene
nlrb5
- ID
- ZDB-GENE-081015-5
- Name
- NOD-like receptor family B, member 5
- Symbol
- nlrb5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Located in cytoplasm. Is expressed in several structures, including female organism; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-159P3 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | GenBank:EB781443 (1) | 487 nt | ||
| Genomic | GenBank:CR457482 | 158288 nt |
No data available
- Sun, W., Zhang, X., Qiao, Y., Griffin, N., Zhang, H., Wang, L., Liu, H. (2023) Exposure to PFOA and its novel analogs disrupts lipid metabolism in zebrafish. Ecotoxicology and environmental safety. 259:115020115020
- Newman, M., Hin, N., Pederson, S., Lardelli, M. (2019) Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Molecular brain. 12:43
- Hu, Y.W., Wu, X.M., Ren, S.S., Cao, L., Nie, P., Chang, M.X. (2017) NOD1 deficiency impairs CD44a/Lck as well as PI3K/Akt pathway. Scientific Reports. 7:2979
- Weh, E., Takeuchi, H., Muheisen, S., Haltiwanger, R.S., Semina, E.V. (2017) Functional characterization of zebrafish orthologs of the human Beta 3-Glucosyltransferase B3GLCT gene mutated in Peters Plus Syndrome. PLoS One. 12:e0184903
- Howe, K., Schiffer, P.H., Zielinski, J., Wiehe, T., Laird, G.K., Marioni, J.C., Soylemez, O., Kondrashov, F., Leptin, M. (2016) Structure and evolutionary history of a large family of NLR proteins in the zebrafish. Open Biology. 6(4):160009
- Hu, Y.W., Yu, Z.L., Xue, N.N., Nie, P., Chang, M.X. (2014) Expression and protective role of two novel NACHT-containing proteins in pathogen infection. Developmental and comparative immunology. 46(2):323-32
- Laing, K.J., Purcell, M.K., Winton, J.R., and Hansen, J.D. (2008) A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish. BMC Evolutionary Biology. 8:42
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