Gene
wnt3
- ID
- ZDB-GENE-081003-1
- Name
- wingless-type MMTV integration site family, member 3
- Symbol
- wnt3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within cloaca development and thalamus development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including basal plate midbrain region; brain; midbrain hindbrain boundary neural tube; posterior neural tube; and presumptive diencephalon. Human ortholog(s) of this gene implicated in tetraamelia syndrome 1. Orthologous to human WNT3 (Wnt family member 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Baranowska Körberg et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| tetraamelia syndrome 1 | Alliance | ?Tetra-amelia syndrome 1 | 273395 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Wnt | Wnt-3 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:B0LK22
|
355 |
Interactions and Pathways
No data available
Plasmids