Gene
skilb
- ID
- ZDB-GENE-080723-40
- Name
- SKI-like proto-oncogene b
- Symbol
- skilb Nomenclature History
- Previous Names
-
- zgc:193698
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have SMAD binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of BMP signaling pathway; negative regulation of transcription by RNA polymerase II; and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to localize to nucleus and transcription factor complex. Orthologous to human SKIL (SKI like proto-oncogene).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003380 | SKI/SNO/DAC domain |
| Domain | IPR014890 | c-SKI SMAD4-binding domain |
| Family | IPR023216 | Transcription regulator SKI/SnoN |
| Homologous_superfamily | IPR009061 | Putative DNA-binding domain superfamily |
| Homologous_superfamily | IPR010919 | SAND-like domain superfamily |
| Homologous_superfamily | IPR037000 | Ski-like, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | c-SKI SMAD4-binding domain | Putative DNA-binding domain superfamily | SAND-like domain superfamily | Ski-like, DNA-binding domain superfamily | SKI/SNO/DAC domain | Transcription regulator SKI/SnoN |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FGJ1
|
624 | ||||||
|
UniProtKB:B3DGU8
|
629 |
Interactions and Pathways
No data available
Plasmids
No data available