Gene

atp2b1b

ID

ZDB-GENE-080409-1

Name

ATPase plasma membrane Ca2+ transporting 1b

Symbol

atp2b1b Nomenclature History

Previous Names

pmca1b (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have PDZ domain binding activity and calcium transmembrane transporter activity, phosphorylative mechanism. Predicted to be involved in regulation of cytosolic calcium ion concentration. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in blood; eye; liver; and pleuroperitoneal region. Orthologous to human ATP2B1 (ATPase plasma membrane Ca2+ transporting 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atp2b1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Intellectual developmental disorder, autosomal dominant 66	619910

Associated With atp2b1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004014	Cation-transporting P-type ATPase, N-terminal
Domain	IPR006068	Cation-transporting P-type ATPase, C-terminal
Domain	IPR022141	Plasma membrane calcium transporting P-type ATPase, C-terminal
Domain	IPR044492	P-type ATPase, haloacid dehalogenase domain
Family	IPR001757	P-type ATPase
Family	IPR006408	P-type ATPase, subfamily IIB
Homologous_superfamily	IPR008250	P-type ATPase, A domain superfamily
Homologous_superfamily	IPR023214	HAD superfamily
Homologous_superfamily	IPR023298	P-type ATPase, transmembrane domain superfamily
Homologous_superfamily	IPR023299	P-type ATPase, cytoplasmic domain N
Homologous_superfamily	IPR036412	HAD-like superfamily
PTM	IPR018303	P-type ATPase, phosphorylation site

Domain Details Per Protein

Protein	Length	Cation-transporting P-type ATPase, C-terminal	Cation-transporting P-type ATPase, N-terminal	HAD-like superfamily	HAD superfamily	Plasma membrane calcium transporting P-type ATPase, C-terminal	P-type ATPase	P-type ATPase, A domain superfamily	P-type ATPase, cytoplasmic domain N	P-type ATPase, haloacid dehalogenase domain	P-type ATPase, phosphorylation site	P-type ATPase, subfamily IIB	P-type ATPase, transmembrane domain superfamily
UniProtKB:B2CZB7 InterPro	1240
UniProtKB:A0A8M3APN2 InterPro	1240
UniProtKB:A0A8M9PUY9 InterPro	896

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	atp2b1b-201 (1) Ensembl	Ensembl	4,711 nt	Select Tool
mRNA	atp2b1b-202 (1) Ensembl	Ensembl	744 nt	Select Tool
mRNA	atp2b1b-203 (1) Ensembl	Ensembl	1,292 nt	Select Tool
mRNA	atp2b1b-204 (1) Ensembl	Ensembl	765 nt	Select Tool
mRNA	atp2b1b-205 (1) Ensembl	Ensembl	647 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations