Gene

acsm3

ID

ZDB-GENE-080220-22

Name

acyl-CoA synthetase medium chain family member 3

Symbol

acsm3 Nomenclature History

Previous Names

zgc:172040

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable fatty acid ligase activity and fatty-acyl-CoA synthase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human ACSM3 (acyl-CoA synthetase medium chain family member 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With acsm3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{?Hypertension, essential}

Associated With acsm3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020845	AMP-binding, conserved site
Domain	IPR000873	AMP-dependent synthetase/ligase domain
Domain	IPR025110	AMP-binding enzyme, C-terminal domain
Family	IPR051087	Mitochondrial Acyl-CoA Synthetase Medium-Chain
Homologous_superfamily	IPR042099	ANL, N-terminal domain
Homologous_superfamily	IPR045851	AMP-binding enzyme, C-terminal domain superfamily