Gene

ifngr1l

ID

ZDB-GENE-071120-8

Name

interferon gamma receptor 1-like

Symbol

ifngr1l Nomenclature History

Previous Names

crfb13
ifngr1-1
IFNGR1-1 (1)
si:ch211-165e15.2

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in asthma; hepatitis B; primary immunodeficiency disease; and tuberculosis. Is expressed in brain; cardiovascular system; gill; muscle; and pleuroperitoneal region. Orthologous to human IFNGR1 (interferon gamma receptor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ifngr1l Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
immunodeficiency 27A	Alliance	Immunodeficiency 27A, mycobacteriosis, AR	209950
immunodeficiency 27B	Alliance	Immunodeficiency 27B, mycobacteriosis, AD	615978
		{H. pylori infection, susceptibility to}	600263
		{Hepatitis B virus infection, susceptibility to}	610424
		{Tuberculosis infection, protection against}	607948
		{Tuberculosis, susceptibility to}	607948

Associated With ifngr1l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017948	Transforming growth factor beta, conserved site
Domain	IPR001839	Transforming growth factor-beta, C-terminal
Domain	IPR003961	Fibronectin type III
Family	IPR015615	Transforming growth factor-beta-related
Family	IPR050650	Type II Cytokine and Tissue Factor Receptors
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR029034	Cystine-knot cytokine
Homologous_superfamily	IPR036116	Fibronectin type III superfamily