Gene

ifngr1l

ID

ZDB-GENE-071120-8

Name

interferon gamma receptor 1-like

Symbol

ifngr1l Nomenclature History

Previous Names

crfb13
ifngr1-1
IFNGR1-1 (1)
si:ch211-165e15.2

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to enable cytokine activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and positive regulation of osteoblast differentiation. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space and plasma membrane. Is expressed in brain; cardiovascular system; gill; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in asthma; hepatitis B; immunodeficiency 27A; immunodeficiency 27B; and tuberculosis. Orthologous to human IFNGR1 (interferon gamma receptor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ifngr1l Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
immunodeficiency 27A	Alliance	Immunodeficiency 27A, mycobacteriosis, AR	209950
immunodeficiency 27B	Alliance	Immunodeficiency 27B, mycobacteriosis, AD	615978
		{H. pylori infection, susceptibility to}	600263
		{Hepatitis B virus infection, susceptibility to}	610424
		{Tuberculosis infection, protection against}	607948
		{Tuberculosis, susceptibility to}	607948

Associated With ifngr1l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017948	Transforming growth factor beta, conserved site
Domain	IPR001839	Transforming growth factor-beta, C-terminal
Domain	IPR003961	Fibronectin type III
Family	IPR015615	Transforming growth factor-beta-related
Family	IPR050650	Type II Cytokine and Tissue Factor Receptors
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR029034	Cystine-knot cytokine
Homologous_superfamily	IPR036116	Fibronectin type III superfamily