Gene

hbl1

ID

ZDB-GENE-070912-285

Name

hexose-binding lectin 1

Symbol

hbl1 Nomenclature History

Previous Names

mbl (1)
si:ch211-284o19.2

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have monosaccharide binding activity. Predicted to be involved in developmental process. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); fungal infectious disease (multiple); liver disease (multiple); lung disease (multiple); and vasculitis (multiple). Orthologous to several human genes including MBL2 (mannose binding lectin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hbl1 Human Ortholog

No data available

Associated With hbl1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018378	C-type lectin, conserved site
Domain	IPR001304	C-type lectin-like
Family	IPR050801	Calcium-Dependent Lectins in Immunity and Development
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Repeat	IPR008160	Collagen triple helix repeat

Domain Details Per Protein

Protein	Length	Calcium-Dependent Lectins in Immunity and Development	Collagen triple helix repeat	C-type lectin, conserved site	C-type lectin fold	C-type lectin-like	C-type lectin-like/link domain superfamily
UniProtKB:A0A8M3AQC7 InterPro	297
UniProtKB:A0A8M9PXC5 InterPro	296
UniProtKB:E9QHK9 InterPro	254

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	hbl1-202 (1) Ensembl	Ensembl		1,010 nt	Select Tool ZFIN BLAST
mRNA	zmp:0000000729-201 (1) Ensembl	Ensembl		291 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations