Gene
wdfy3
- ID
- ZDB-GENE-070705-153
- Name
- WD repeat and FYVE domain containing 3
- Symbol
- wdfy3 Nomenclature History
- Previous Names
-
- si:ch211-259k10.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. Orthologous to human WDFY3 (WD repeat and FYVE domain containing 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal dominant microcephaly 18 | Alliance | ?Microcephaly 18, primary, autosomal dominant | 617520 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR000306 | FYVE zinc finger |
| Domain | IPR000409 | BEACH domain |
| Domain | IPR017455 | Zinc finger, FYVE-related |
| Domain | IPR023362 | PH-BEACH domain |
| Family | IPR051944 | BEACH domain-containing protein |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Homologous_superfamily | IPR036372 | BEACH domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | BEACH domain | BEACH domain-containing protein | BEACH domain superfamily | Concanavalin A-like lectin/glucanase domain superfamily | FYVE zinc finger | PH-BEACH domain | PH-like domain superfamily | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BCS8
|
3525 | ||||||||||||||||
|
UniProtKB:A0A8M6Z0T9
|
3496 | ||||||||||||||||
|
UniProtKB:A0A8M6YZB2
|
3497 | ||||||||||||||||
|
UniProtKB:A0A8M6Z6H7
|
3523 | ||||||||||||||||
|
UniProtKB:A0A8M1QLH0
|
3505 | ||||||||||||||||
|
UniProtKB:A0A8M9PYD4
|
113 | ||||||||||||||||
|
UniProtKB:A0A8M6YYF4
|
3524 |
Interactions and Pathways
No data available
Plasmids
No data available