Gene
jam3a
- ID
- ZDB-GENE-070424-177
- Name
- junctional adhesion molecule 3a
- Symbol
- jam3a Nomenclature History
- Previous Names
-
- jamc2 (1)
- si:ch211-277g22.3
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable cell-cell adhesion mediator activity. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be part of protein complex involved in cell adhesion. Predicted to be active in cell-cell contact zone and plasma membrane. Is expressed in brain; lateral line primordium; and neural tube. Orthologous to human JAM3 (junctional adhesion molecule 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Powell et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hemorrhagic destruction of the brain, subependymal calcification, and cataracts | 613730 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Family | IPR042974 | Junctional adhesion molecule C |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Junctional adhesion molecule C |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QYW3
|
301 | ||||||
|
UniProtKB:A0A8M1Q7B3
|
301 |
Interactions and Pathways
No data available
Plasmids