ZFIN ID: ZDB-GENE-070424-177
Gene Name: junctional adhesion molecule 3a
Gene Symbol: jam3a    Nomenclature History

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Previous Names: jamc2 (1), si:ch211-277g22.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in cell adhesion. Predicted to localize to integral component of membrane. Is expressed in brain; lateral line primordium; and neural tube. Orthologous to human JAM3 (junctional adhesion molecule 3).
Genome Resources: Alliance (1),  Gene:797651 (1),  Ensembl(GRCz11):ENSDARG00000114589 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH jam3a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hemorrhagic destruction of the brain, subependymal calcification, and cataracts 613730
DISEASE ASSOCIATED WITH jam3a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell adhesion (more)
Cellular Component integral component of membrane (more)
Molecular Function protein heterodimerization activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA jam3a-201 (1)    Ensembl 2152
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-jam3a monoclonal IgG1 , k Mouse 1
CONSTRUCTS WITH SEQUENCES FROM jam3a No data available
MARKER RELATIONSHIPS
jam3a Contained in: [BAC] CH211-66O10 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_001338087 (1) 2147 nt
Genomic GenBank:CR626890 (1) 211127 nt Blast at MegaBLAST
Polypeptide UniProtKB:F1QYW3 (1) 301 aa
Sequence Information (all 15)
ORTHOLOGY for jam3a ( Chr: 15 )
CITATIONS (17)