Gene

mavs

ID

ZDB-GENE-070112-1402

Name

mitochondrial antiviral signaling protein

Symbol

mavs Nomenclature History

Previous Names

wu:fj20d04
zgc:158392

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Exhibits protein heterodimerization activity. Involved in cytoplasmic pattern recognition receptor signaling pathway in response to virus; regulation of transcription, DNA-templated; and response to bacterium. Localizes to mitochondrion. Orthologous to human MAVS (mitochondrial antiviral signaling protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mavs Human Ortholog

No data available

Associated With mavs Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR031964	Caspase recruitment domain
Domain	IPR042144	IPS1, CARD domain
Family	IPR052787	Mitochondrial antiviral-signaling domain-containing protein
Homologous_superfamily	IPR011029	Death-like domain superfamily

Domain Details Per Protein

Protein	Length	Caspase recruitment domain	Death-like domain superfamily	IPS1, CARD domain	Mitochondrial antiviral-signaling domain-containing protein
UniProtKB:F1REK4 InterPro	585
UniProtKB:B8A4W7 InterPro	364

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mavs-201 (1) Ensembl	Ensembl	4,397 nt	Select Tool ZFIN BLAST
mRNA	mavs-202 (1) Ensembl	Ensembl	4,108 nt	Select Tool ZFIN BLAST
mRNA	mavs-203 (1) Ensembl	Ensembl	790 nt	Select Tool ZFIN BLAST
mRNA	mavs-205 (1) Ensembl	Ensembl	744 nt	Select Tool ZFIN BLAST
mRNA	mavs-206 (1) Ensembl	Ensembl	4,559 nt	Select Tool ZFIN BLAST
ncRNA	mavs-004 (1) Ensembl	Ensembl	574 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations